Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset

NX Tritsch, A Rodriguez-Contreras, Tom Crins, HC Wang, Gerard Borst, DE Bergles

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Abstract

We found rat central auditory neurons to fire action potentials in a precise sequence of mini-bursts before the age of hearing onset. This stereotyped pattern was initiated by hair cells in the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca2+ spike. By generating theta-like activity, hair cells may limit the influence of synaptic depression in developing auditory circuits and promote consolidation of synapses.
Original languageUndefined/Unknown
Pages (from-to)1050-1052
Number of pages3
JournalNature Neuroscience
Volume13
Issue number9
DOIs
Publication statusPublished - 2010

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