Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset

NX Tritsch; A Rodriguez-Contreras; Tom Crins; HC Wang; Gerard Borst; DE Bergles

doi:10.1038/nn.2604

Calcium action potentials in hair cells pattern auditory neuron activity before hearing onset

NX Tritsch, A Rodriguez-Contreras, Tom Crins, HC Wang, Gerard Borst, DE Bergles

Research output: Contribution to journal › Article › Academic › peer-review

170 Citations (Scopus)

Abstract

We found rat central auditory neurons to fire action potentials in a precise sequence of mini-bursts before the age of hearing onset. This stereotyped pattern was initiated by hair cells in the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca2+ spike. By generating theta-like activity, hair cells may limit the influence of synaptic depression in developing auditory circuits and promote consolidation of synapses.

Original language	Undefined/Unknown
Pages (from-to)	1050-1052
Number of pages	3
Journal	Nature Neuroscience
Volume	13
Issue number	9
DOIs	https://doi.org/10.1038/nn.2604
Publication status	Published - 2010

Research programs

EMC ONWAR-01-94-01
EMC OR-01-62-02

Access to Document

10.1038/nn.2604

http://hdl.handle.net/1765/28317

Cite this

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abstract = "We found rat central auditory neurons to fire action potentials in a precise sequence of mini-bursts before the age of hearing onset. This stereotyped pattern was initiated by hair cells in the cochlea, which trigger brief bursts of action potentials in auditory neurons each time they fire a Ca2+ spike. By generating theta-like activity, hair cells may limit the influence of synaptic depression in developing auditory circuits and promote consolidation of synapses.",

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AU - Borst, Gerard

AU - Bergles, DE

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