Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

EAM Calvier; TT Nguyen; TN Johnson; A Rostami-Hodjegan; Dick Tibboel; EHJ Krekels; Catherijne Knibbe

doi:10.1007/s11095-018-2487-1

Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

EAM Calvier
, TT Nguyen
, TN Johnson
, A Rostami-Hodjegan
, Dick Tibboel
, EHJ Krekels
, Catherijne Knibbe

Intensive Care

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

10 Citations (Scopus)

29 Downloads (Pure)

Original language	Undefined/Unknown
Article number	Unsp 209
Journal	Pharmaceutical Research
Volume	35
Issue number	11
DOIs	https://doi.org/10.1007/s11095-018-2487-1
Publication status	Published - 2018

Research programs

EMC OR-01

Access to Document

10.1007/s11095-018-2487-1

Calvier2018_Article_CanPopulationModellingPrincipl.pdfFinal published version, 1.15 MB

http://hdl.handle.net/1765/114304

Cite this

Calvier, EAM., Nguyen, TT., Johnson, TN., Rostami-Hodjegan, A., Tibboel, D., Krekels, EHJ., & Knibbe, C. (2018). Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory. Pharmaceutical Research, 35(11), Article Unsp 209. https://doi.org/10.1007/s11095-018-2487-1

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AU - Tibboel, Dick

AU - Krekels, EHJ

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