Can we predict the future of patients with liver cirrhosis using volumetrics?

Marten A. Lantinga*, Laurens A. van Kleef

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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In the article on computed tomography (CT) volumetrics in liver cirrhosis Romero-Cristóbal et al. investigated the relationship between changes in liver-spleen volume and features of cirrhosis in patients with compensated or decompensated liver cirrhosis who either underwent liver transplantation or partial hepatectomy for hepatocellular carcinoma (HCC)

The authors showed in this Spanish cross-sectional single center study that changes in liver volume, liver segmental volume ratio and liver-spleen volume ratio evaluated by CT reflected the course of disease progression through the different stages of liver cirrhosis. Specific changes in volumetrics appeared to be related to compensated cirrhosis, compensated cirrhosis with development of portal hypertension and decompensated liver cirrhosis. Interestingly, these changes were independent of the predictive value of histological level of liver fibrosis. The authors concluded that the observed changes in liver and spleen volumes correlate with the different clinical stages in the course of liver disease progression. In turn, this would suggest that CT volumetrics of liver and spleen could be a readily available non-invasive tool to provide prognostic information in cirrhotic patients. [...]
Original languageEnglish
Pages (from-to)791-792
Number of pages2
JournalUnited European Gastroenterology Journal
Issue number8
Early online date12 Sept 2022
Publication statusPublished - 12 Sept 2022

Bibliographical note

© 2022 The Authors. United European Gastroenterology Journal published by Wiley Periodicals LLC. on behalf of United European Gastroenterology.


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