Capturing Patient Value in an Economic Evaluation

Fiona Koster; Marc R Kok; Deirisa Lopes Barreto; Angelique E A M Weel-Koenders

doi:10.1002/acr.25229

Capturing Patient Value in an Economic Evaluation

Fiona Koster^*, Marc R Kok, Deirisa Lopes Barreto, Angelique E A M Weel-Koenders

^*Corresponding author for this work

Health Technology Assessment (HTA)

Research output: Contribution to journal › Article › Academic › peer-review

44 Downloads (Pure)

Abstract

OBJECTIVE:

Economic evaluations predominantly use generic outcomes, such as EuroQol-5 Dimension (EQ-5D), to assess the health status. However, because of the generic nature, they are less suitable to capture the quality of life of patients with specific conditions. Given the transition to patient-centered (remote) care delivery, this study aims to evaluate the possibility to use disease-specific measures in a cost-effectiveness analysis (CEA).

METHODS:

A real-life cohort from Maasstad Hospital (2020-2021) in the Netherlands, with 772 Rheumatoid Arthritis (RA) patients, was used to assess the cost-effectiveness of electronic consultations (e-consultations) compared with face-to-face consultations. The Incremental Cost-Effectiveness Ratio (ICER) based on the generic EQ-5D was compared with ICER's based on RA specific measures; Rheumatoid Arthritis Impact of Disease (RAID) and Health Assessment Questionnaire-Disability Index (HAQ-DI). To compare the cost-effectiveness of these different measures, HAQ-DI and RAID were expressed in QALYs via estimated conversion equations.

CONCLUSIONS:

The conventional ICER (e.g. EQ-5D) indicates that e-consultations are cost-effective with cost savings of - €161k per QALY gained for a prevalent RA cohort treated in a secondary trainee hospital. RA specific measures show similar results, with ICER's of - €163k per HAQ-DI(QALY) and - €223k per RAID(QALY) gained. RA specific measures capture patient-relevant domains and offer the opportunity to improve the assessment and treatment of the disease impact.

DISCUSSION:

Disease-specific patient-reported outcome measures (PROMs) offer a promising alternative for traditional measures in economic evaluations, capturing patient-relevant domains more comprehensively. As PROMs are increasingly applied in clinical practice, the next step entails modelling of a RA patient-wide conversion equation to implement PROMs in economic evaluations. This article is protected by copyright. All rights reserved.

Original language	English
Pages (from-to)	191-199
Number of pages	9
Journal	Arthritis Care & Research
Volume	76
Issue number	2
Early online date	Dec 2023
DOIs	https://doi.org/10.1002/acr.25229
Publication status	Published - Feb 2024

Bibliographical note

Publisher Copyright:
© 2023 The Authors. Arthritis Care & Research published by Wiley Periodicals LLC on behalf of American College of Rheumatology.

Access to Document

10.1002/acr.25229Licence: CC BY-NC-ND

Capturing Patient Value in an Economic EvaluationFinal published version, 409 KBLicence: CC BY-NC-ND

Cite this

@article{b9f216eb766946bb8931e74de2be0f08,

title = "Capturing Patient Value in an Economic Evaluation",

abstract = "OBJECTIVE: Economic evaluations predominantly use generic outcomes, such as EuroQol-5 Dimension (EQ-5D), to assess the health status. However, because of the generic nature, they are less suitable to capture the quality of life of patients with specific conditions. Given the transition to patient-centered (remote) care delivery, this study aims to evaluate the possibility to use disease-specific measures in a cost-effectiveness analysis (CEA).METHODS: A real-life cohort from Maasstad Hospital (2020-2021) in the Netherlands, with 772 Rheumatoid Arthritis (RA) patients, was used to assess the cost-effectiveness of electronic consultations (e-consultations) compared with face-to-face consultations. The Incremental Cost-Effectiveness Ratio (ICER) based on the generic EQ-5D was compared with ICER's based on RA specific measures; Rheumatoid Arthritis Impact of Disease (RAID) and Health Assessment Questionnaire-Disability Index (HAQ-DI). To compare the cost-effectiveness of these different measures, HAQ-DI and RAID were expressed in QALYs via estimated conversion equations.CONCLUSIONS: The conventional ICER (e.g. EQ-5D) indicates that e-consultations are cost-effective with cost savings of - €161k per QALY gained for a prevalent RA cohort treated in a secondary trainee hospital. RA specific measures show similar results, with ICER's of - €163k per HAQ-DI(QALY) and - €223k per RAID(QALY) gained. RA specific measures capture patient-relevant domains and offer the opportunity to improve the assessment and treatment of the disease impact.DISCUSSION: Disease-specific patient-reported outcome measures (PROMs) offer a promising alternative for traditional measures in economic evaluations, capturing patient-relevant domains more comprehensively. As PROMs are increasingly applied in clinical practice, the next step entails modelling of a RA patient-wide conversion equation to implement PROMs in economic evaluations. This article is protected by copyright. All rights reserved.",

author = "Fiona Koster and Kok, {Marc R} and {Lopes Barreto}, Deirisa and Weel-Koenders, {Angelique E A M}",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors. Arthritis Care & Research published by Wiley Periodicals LLC on behalf of American College of Rheumatology.",

year = "2024",

month = feb,

doi = "10.1002/acr.25229",

language = "English",

volume = "76",

pages = "191--199",

journal = "Arthritis Care & Research",

issn = "2151-464X",

publisher = "John Wiley & Sons Inc.",

number = "2",

}

TY - JOUR

T1 - Capturing Patient Value in an Economic Evaluation

AU - Koster, Fiona

AU - Kok, Marc R

AU - Lopes Barreto, Deirisa

AU - Weel-Koenders, Angelique E A M

PY - 2024/2

Y1 - 2024/2

N2 - OBJECTIVE: Economic evaluations predominantly use generic outcomes, such as EuroQol-5 Dimension (EQ-5D), to assess the health status. However, because of the generic nature, they are less suitable to capture the quality of life of patients with specific conditions. Given the transition to patient-centered (remote) care delivery, this study aims to evaluate the possibility to use disease-specific measures in a cost-effectiveness analysis (CEA).METHODS: A real-life cohort from Maasstad Hospital (2020-2021) in the Netherlands, with 772 Rheumatoid Arthritis (RA) patients, was used to assess the cost-effectiveness of electronic consultations (e-consultations) compared with face-to-face consultations. The Incremental Cost-Effectiveness Ratio (ICER) based on the generic EQ-5D was compared with ICER's based on RA specific measures; Rheumatoid Arthritis Impact of Disease (RAID) and Health Assessment Questionnaire-Disability Index (HAQ-DI). To compare the cost-effectiveness of these different measures, HAQ-DI and RAID were expressed in QALYs via estimated conversion equations.CONCLUSIONS: The conventional ICER (e.g. EQ-5D) indicates that e-consultations are cost-effective with cost savings of - €161k per QALY gained for a prevalent RA cohort treated in a secondary trainee hospital. RA specific measures show similar results, with ICER's of - €163k per HAQ-DI(QALY) and - €223k per RAID(QALY) gained. RA specific measures capture patient-relevant domains and offer the opportunity to improve the assessment and treatment of the disease impact.DISCUSSION: Disease-specific patient-reported outcome measures (PROMs) offer a promising alternative for traditional measures in economic evaluations, capturing patient-relevant domains more comprehensively. As PROMs are increasingly applied in clinical practice, the next step entails modelling of a RA patient-wide conversion equation to implement PROMs in economic evaluations. This article is protected by copyright. All rights reserved.

AB - OBJECTIVE: Economic evaluations predominantly use generic outcomes, such as EuroQol-5 Dimension (EQ-5D), to assess the health status. However, because of the generic nature, they are less suitable to capture the quality of life of patients with specific conditions. Given the transition to patient-centered (remote) care delivery, this study aims to evaluate the possibility to use disease-specific measures in a cost-effectiveness analysis (CEA).METHODS: A real-life cohort from Maasstad Hospital (2020-2021) in the Netherlands, with 772 Rheumatoid Arthritis (RA) patients, was used to assess the cost-effectiveness of electronic consultations (e-consultations) compared with face-to-face consultations. The Incremental Cost-Effectiveness Ratio (ICER) based on the generic EQ-5D was compared with ICER's based on RA specific measures; Rheumatoid Arthritis Impact of Disease (RAID) and Health Assessment Questionnaire-Disability Index (HAQ-DI). To compare the cost-effectiveness of these different measures, HAQ-DI and RAID were expressed in QALYs via estimated conversion equations.CONCLUSIONS: The conventional ICER (e.g. EQ-5D) indicates that e-consultations are cost-effective with cost savings of - €161k per QALY gained for a prevalent RA cohort treated in a secondary trainee hospital. RA specific measures show similar results, with ICER's of - €163k per HAQ-DI(QALY) and - €223k per RAID(QALY) gained. RA specific measures capture patient-relevant domains and offer the opportunity to improve the assessment and treatment of the disease impact.DISCUSSION: Disease-specific patient-reported outcome measures (PROMs) offer a promising alternative for traditional measures in economic evaluations, capturing patient-relevant domains more comprehensively. As PROMs are increasingly applied in clinical practice, the next step entails modelling of a RA patient-wide conversion equation to implement PROMs in economic evaluations. This article is protected by copyright. All rights reserved.

UR - http://www.scopus.com/inward/record.url?scp=85179980097&partnerID=8YFLogxK

U2 - 10.1002/acr.25229

DO - 10.1002/acr.25229

M3 - Article

C2 - 37667586

SN - 2151-464X

VL - 76

SP - 191

EP - 199

JO - Arthritis Care & Research

JF - Arthritis Care & Research

IS - 2

ER -

Capturing Patient Value in an Economic Evaluation

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this