TY - JOUR
T1 - Cardiovascular risk assessment of the diabetic patient undergoing major noncardiac surgery
AU - Hoeks, Sanne
AU - Flu, Willem jan
AU - Kuijk, Jan-peter
AU - Bax, J
AU - Poldermans, D
PY - 2009
Y1 - 2009
N2 - Noncardiac Surgery is associated with an increased risk for cardiovascular morbidity and mortality. It is important to stratify the risk of these patients for perioperative cardiac events. Diabetes, a presently rapidly expanding disease, is a major risk factor for cardiovascular morbidity and mortality. Importantly, silent ischemia is more common in diabetic patients than in the general Population. When preoperative risk assessment identifies an increased risk, further cardiac testing is warranted. The Most Commonly used stress tests for detecting cardiac ischemia is treadmill or bicycle ergometry. However, patients undergoing noncardiac Surgery frequently have limited exercise capacity due to co-morbidities. Pharmacologic testing, Such as dobutamine stress echocardiography and dipyridamole myocardial perfusion scintigraphy can be performed in patients with limited exercise capacity. Non-invasive stress testing Should be considered, especially in diabetic patients, to detect asymptomatic coronary artery disease. Furthermore, when an increased cardiac risk is assessed, two strategies could be used to reduce the incidence of perioperative cardiac events: 1) prophylactic coronary revascularization from which the value is still controversial, and 2) pharmacological treatment (with beta-blockers, statins and aspirin), associated with improved post-operative Outcome. (C) 2009 Elsevier Ltd. All rights reserved.
AB - Noncardiac Surgery is associated with an increased risk for cardiovascular morbidity and mortality. It is important to stratify the risk of these patients for perioperative cardiac events. Diabetes, a presently rapidly expanding disease, is a major risk factor for cardiovascular morbidity and mortality. Importantly, silent ischemia is more common in diabetic patients than in the general Population. When preoperative risk assessment identifies an increased risk, further cardiac testing is warranted. The Most Commonly used stress tests for detecting cardiac ischemia is treadmill or bicycle ergometry. However, patients undergoing noncardiac Surgery frequently have limited exercise capacity due to co-morbidities. Pharmacologic testing, Such as dobutamine stress echocardiography and dipyridamole myocardial perfusion scintigraphy can be performed in patients with limited exercise capacity. Non-invasive stress testing Should be considered, especially in diabetic patients, to detect asymptomatic coronary artery disease. Furthermore, when an increased cardiac risk is assessed, two strategies could be used to reduce the incidence of perioperative cardiac events: 1) prophylactic coronary revascularization from which the value is still controversial, and 2) pharmacological treatment (with beta-blockers, statins and aspirin), associated with improved post-operative Outcome. (C) 2009 Elsevier Ltd. All rights reserved.
U2 - 10.1016/j.beem.2009.01.002
DO - 10.1016/j.beem.2009.01.002
M3 - Article
VL - 23
SP - 361
EP - 373
JO - Best Practice and Research in Clinical Endocrinology and Metabolism
JF - Best Practice and Research in Clinical Endocrinology and Metabolism
SN - 1521-690X
IS - 3
ER -