Cataract extraction and age-related macular degeneration: The rotterdam study

J. R. Vingerling; C. C.W. Klaver; A. Hofman; P. T.V.M. De Jong

Cataract extraction and age-related macular degeneration: The rotterdam study

J. R. Vingerling^*, C. C.W. Klaver, A. Hofman, P. T.V.M. De Jong

^*Corresponding author for this work

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Abstract

Purpose: To test the hypothesis of recent reports suggesting that cataractextraction increases risk of neovascular age-related maculopathy (AMD), we studied the association between cataractextraction and AMD in a general population. Methods: Of 6417 (80%) participants of the population-based Rotterdam Study, complete data were available on cataractextraction and maculopathy grading. Only right eyes were used in the analysis. Results: Prevalence of cataractextraction was 3.8%; prevalence of atrophie or neovascular AMD was 1.2%. Cataractextraction was not associated with AMD; the age and sex adjusted risk of AMD was 0.9 (95%CI 0.4-2.0). More specifically, the risk of neovascular AMD was 0.6 (95%CI 0.1-2.6), and of atrophie AMD 1.2 (0.4-3.0). Conclusion: We find that, in a general population, cataractextraction is not associated with increased risk of AMD.

Original language	English
Pages (from-to)	S465
Journal	Investigative Ophthalmology and Visual Science
Volume	38
Issue number	4
Publication status	Published - 1997

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title = "Cataract extraction and age-related macular degeneration: The rotterdam study",

abstract = "Purpose: To test the hypothesis of recent reports suggesting that cataractextraction increases risk of neovascular age-related maculopathy (AMD), we studied the association between cataractextraction and AMD in a general population. Methods: Of 6417 (80%) participants of the population-based Rotterdam Study, complete data were available on cataractextraction and maculopathy grading. Only right eyes were used in the analysis. Results: Prevalence of cataractextraction was 3.8%; prevalence of atrophie or neovascular AMD was 1.2%. Cataractextraction was not associated with AMD; the age and sex adjusted risk of AMD was 0.9 (95%CI 0.4-2.0). More specifically, the risk of neovascular AMD was 0.6 (95%CI 0.1-2.6), and of atrophie AMD 1.2 (0.4-3.0). Conclusion: We find that, in a general population, cataractextraction is not associated with increased risk of AMD.",

author = "Vingerling, {J. R.} and Klaver, {C. C.W.} and A. Hofman and {De Jong}, {P. T.V.M.}",

year = "1997",

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T1 - Cataract extraction and age-related macular degeneration

T2 - The rotterdam study

AU - Vingerling, J. R.

AU - Klaver, C. C.W.

AU - Hofman, A.

AU - De Jong, P. T.V.M.

PY - 1997

Y1 - 1997

N2 - Purpose: To test the hypothesis of recent reports suggesting that cataractextraction increases risk of neovascular age-related maculopathy (AMD), we studied the association between cataractextraction and AMD in a general population. Methods: Of 6417 (80%) participants of the population-based Rotterdam Study, complete data were available on cataractextraction and maculopathy grading. Only right eyes were used in the analysis. Results: Prevalence of cataractextraction was 3.8%; prevalence of atrophie or neovascular AMD was 1.2%. Cataractextraction was not associated with AMD; the age and sex adjusted risk of AMD was 0.9 (95%CI 0.4-2.0). More specifically, the risk of neovascular AMD was 0.6 (95%CI 0.1-2.6), and of atrophie AMD 1.2 (0.4-3.0). Conclusion: We find that, in a general population, cataractextraction is not associated with increased risk of AMD.

AB - Purpose: To test the hypothesis of recent reports suggesting that cataractextraction increases risk of neovascular age-related maculopathy (AMD), we studied the association between cataractextraction and AMD in a general population. Methods: Of 6417 (80%) participants of the population-based Rotterdam Study, complete data were available on cataractextraction and maculopathy grading. Only right eyes were used in the analysis. Results: Prevalence of cataractextraction was 3.8%; prevalence of atrophie or neovascular AMD was 1.2%. Cataractextraction was not associated with AMD; the age and sex adjusted risk of AMD was 0.9 (95%CI 0.4-2.0). More specifically, the risk of neovascular AMD was 0.6 (95%CI 0.1-2.6), and of atrophie AMD 1.2 (0.4-3.0). Conclusion: We find that, in a general population, cataractextraction is not associated with increased risk of AMD.

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IS - 4

ER -

Cataract extraction and age-related macular degeneration: The rotterdam study

Abstract

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