Cataract extraction and age-related macular degeneration: The rotterdam study

J. R. Vingerling*, C. C.W. Klaver, A. Hofman, P. T.V.M. De Jong

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)


Purpose: To test the hypothesis of recent reports suggesting that cataractextraction increases risk of neovascular age-related maculopathy (AMD), we studied the association between cataractextraction and AMD in a general population. Methods: Of 6417 (80%) participants of the population-based Rotterdam Study, complete data were available on cataractextraction and maculopathy grading. Only right eyes were used in the analysis. Results: Prevalence of cataractextraction was 3.8%; prevalence of atrophie or neovascular AMD was 1.2%. Cataractextraction was not associated with AMD; the age and sex adjusted risk of AMD was 0.9 (95%CI 0.4-2.0). More specifically, the risk of neovascular AMD was 0.6 (95%CI 0.1-2.6), and of atrophie AMD 1.2 (0.4-3.0). Conclusion: We find that, in a general population, cataractextraction is not associated with increased risk of AMD.

Original languageEnglish
Pages (from-to)S465
JournalInvestigative Ophthalmology and Visual Science
Issue number4
Publication statusPublished - 1997

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© Copyright 2012 Elsevier B.V., All rights reserved.


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