CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents

Tom Reuvekamp; Lok Lam Ngai; Daphne den Hartog; Jannemieke Carbaat-Ham; Mona M.H.E. Fayed; Willemijn J. Scholten; Tim R. Mocking; Dana A. Chitu; Thomas Pabst; Saskia K. Klein; Georg Stussi; Laimonas Griskevicius; Dimitri Breems; Danielle van Lammeren-Venema; Rinske Boersma; Gert J. Ossenkoppele; Arjan A. van de Loosdrecht; Costa Bachas; Gerwin Huls; David C. de Leeuw; Jacqueline Cloos

doi:10.1038/s41375-025-02539-0

CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents

Tom Reuvekamp
, Lok Lam Ngai
, Daphne den Hartog
, Jannemieke Carbaat-Ham
, Mona M.H.E. Fayed
, Willemijn J. Scholten
, Tim R. Mocking
, Dana A. Chitu
, Thomas Pabst
, Saskia K. Klein
, Georg Stussi
, Laimonas Griskevicius
, Dimitri Breems
, Danielle van Lammeren-Venema
, Rinske Boersma
, Gert J. Ossenkoppele
, Arjan A. van de Loosdrecht
, Costa Bachas
, Gerwin Huls
, David C. de Leeuw

Jacqueline Cloos^*

^*Corresponding author for this work

Hematology

Vrije Universiteit Amsterdam
Amsterdam UMC
University of Amsterdam
University of Bern
University Medical Centre Groningen
Meander Hospital Amersfoort
Ospedale Regionale (Bellinzona)
Vilnius University
Ziekenhuis Netwerk Antwerpen (ZNA)
Haga Ziekenhuis
Amphia Hospital

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

10 Citations (Scopus)

84 Downloads (Pure)

Original language	English
Pages (from-to)	972-975
Number of pages	4
Journal	Leukemia
Volume	39
Issue number	4
DOIs	https://doi.org/10.1038/s41375-025-02539-0
Publication status	Published - Apr 2025

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Reuvekamp, T., Ngai, L. L., den Hartog, D., Carbaat-Ham, J., Fayed, M. M. H. E., Scholten, W. J., Mocking, T. R., Chitu, D. A., Pabst, T., Klein, S. K., Stussi, G., Griskevicius, L., Breems, D., van Lammeren-Venema, D., Boersma, R., Ossenkoppele, G. J., van de Loosdrecht, A. A., Bachas, C., Huls, G., ... Cloos, J. (2025). CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents. Leukemia, 39(4), 972-975. https://doi.org/10.1038/s41375-025-02539-0

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title = "CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents",

author = "Tom Reuvekamp and Ngai, \{Lok Lam\} and \{den Hartog\}, Daphne and Jannemieke Carbaat-Ham and Fayed, \{Mona M.H.E.\} and Scholten, \{Willemijn J.\} and Mocking, \{Tim R.\} and Chitu, \{Dana A.\} and Thomas Pabst and Klein, \{Saskia K.\} and Georg Stussi and Laimonas Griskevicius and Dimitri Breems and \{van Lammeren-Venema\}, Danielle and Rinske Boersma and Ossenkoppele, \{Gert J.\} and \{van de Loosdrecht\}, \{Arjan A.\} and Costa Bachas and Gerwin Huls and \{de Leeuw\}, \{David C.\} and Jacqueline Cloos",

year = "2025",

month = apr,

doi = "10.1038/s41375-025-02539-0",

language = "English",

volume = "39",

pages = "972--975",

journal = "Leukemia",

issn = "0887-6924",

publisher = "Springer Nature",

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}

Reuvekamp, T, Ngai, LL, den Hartog, D, Carbaat-Ham, J, Fayed, MMHE, Scholten, WJ, Mocking, TR, Chitu, DA, Pabst, T, Klein, SK, Stussi, G, Griskevicius, L, Breems, D, van Lammeren-Venema, D, Boersma, R, Ossenkoppele, GJ, van de Loosdrecht, AA, Bachas, C, Huls, G, de Leeuw, DC & Cloos, J 2025, 'CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents', Leukemia, vol. 39, no. 4, pp. 972-975. https://doi.org/10.1038/s41375-025-02539-0

TY - JOUR

T1 - CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents

AU - Reuvekamp, Tom

AU - Ngai, Lok Lam

AU - den Hartog, Daphne

AU - Carbaat-Ham, Jannemieke

AU - Fayed, Mona M.H.E.

AU - Scholten, Willemijn J.

AU - Mocking, Tim R.

AU - Chitu, Dana A.

AU - Pabst, Thomas

AU - Klein, Saskia K.

AU - Stussi, Georg

AU - Griskevicius, Laimonas

AU - Breems, Dimitri

AU - van Lammeren-Venema, Danielle

AU - Boersma, Rinske

AU - Ossenkoppele, Gert J.

AU - van de Loosdrecht, Arjan A.

AU - Bachas, Costa

AU - Huls, Gerwin

AU - de Leeuw, David C.

AU - Cloos, Jacqueline

PY - 2025/4

Y1 - 2025/4

UR - https://www.scopus.com/pages/publications/86000113671

U2 - 10.1038/s41375-025-02539-0

DO - 10.1038/s41375-025-02539-0

M3 - Comment/Letter to the editor

C2 - 40016301

AN - SCOPUS:86000113671

SN - 0887-6924

VL - 39

SP - 972

EP - 975

JO - Leukemia

JF - Leukemia

IS - 4

ER -

CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents

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