Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement

Ilkka Heinonen; Oana Sorop; Bas van Dalen; RCI Wüst; Jens van de Wouw; Vincent Beer; Yanti Octavia; Richard Duin; Youri Hoogstrate; Lau Blonden; M Alkio; K Anttila; Andrew Stubbs; J Velden; Daphne Merkus; Dirk-jan Duncker

doi:10.1038/s41598-020-68637-4

Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement

Ilkka Heinonen
, Oana Sorop
, Bas van Dalen
, RCI Wüst
, Jens van de Wouw
, Vincent Beer
, Yanti Octavia
, Richard Duin
, Youri Hoogstrate
, Lau Blonden
, M Alkio
, K Anttila
, Andrew Stubbs
, J Velden
, Daphne Merkus
, Dirk-jan Duncker

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

21 Citations (Scopus)

39 Downloads (Pure)

Original language	English
Article number	13173
Journal	Scientific Reports
Volume	10
Issue number	1
DOIs	https://doi.org/10.1038/s41598-020-68637-4
Publication status	Published - 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research programs

EMC COEUR-09
EMC MM-03-24-01
EMC MM-03-49-01

Access to Document

10.1038/s41598-020-68637-4

Repub_129401_O-A.pdfFinal published version, 3.62 MB

Cite this

Heinonen, I., Sorop, O., van Dalen, B., Wüst, RCI., van de Wouw, J., Beer, V., Octavia, Y., Duin, R., Hoogstrate, Y., Blonden, L., Alkio, M., Anttila, K., Stubbs, A., Velden, J., Merkus, D., & Duncker, D. (2020). Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement. Scientific Reports, 10(1), Article 13173. https://doi.org/10.1038/s41598-020-68637-4

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title = "Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement",

author = "Ilkka Heinonen and Oana Sorop and \{van Dalen\}, Bas and RCI W{\"u}st and \{van de Wouw\}, Jens and Vincent Beer and Yanti Octavia and Richard Duin and Youri Hoogstrate and Lau Blonden and M Alkio and K Anttila and Andrew Stubbs and J Velden and Daphne Merkus and Dirk-jan Duncker",

year = "2020",

doi = "10.1038/s41598-020-68637-4",

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Heinonen, I, Sorop, O , van Dalen, B, Wüst, RCI, van de Wouw, J, Beer, V, Octavia, Y, Duin, R, Hoogstrate, Y, Blonden, L, Alkio, M, Anttila, K, Stubbs, A, Velden, J, Merkus, D & Duncker, D 2020, 'Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement', Scientific Reports, vol. 10, no. 1, 13173. https://doi.org/10.1038/s41598-020-68637-4

TY - JOUR

T1 - Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement

AU - Heinonen, Ilkka

AU - Sorop, Oana

AU - van Dalen, Bas

AU - Wüst, RCI

AU - van de Wouw, Jens

AU - Beer, Vincent

AU - Octavia, Yanti

AU - Duin, Richard

AU - Hoogstrate, Youri

AU - Blonden, Lau

AU - Alkio, M

AU - Anttila, K

AU - Stubbs, Andrew

AU - Velden, J

AU - Merkus, Daphne

AU - Duncker, Dirk-jan

PY - 2020

Y1 - 2020

U2 - 10.1038/s41598-020-68637-4

DO - 10.1038/s41598-020-68637-4

M3 - Article

C2 - 32764569

SN - 2045-2322

VL - 10

JO - Scientific Reports

JF - Scientific Reports

IS - 1

M1 - 13173

ER -