Changing Perspectives on the Perinatal Management of Isolated Congenital Diaphragmatic Hernia in Europe

JA Deprest, E Gratacos, K Nicolaides, E Done, T Van Mieghem, L Gucciardo, F Claus, A Debeer, Karel Allegaert, Irwin Reiss, Dick Tibboel

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Congenital diaphragmatic hernia (CDH) should be diagnosed in the prenatal period and prompt referral to a tertiary referral center for imaging, genetic testing, and multidisciplinary counseling. Individual prediction of prognosis is based on the absence of additional anomalies, lung size, and liver herniation. In severe cases, a prenatal endotracheal balloon procedure is currently being offered at specialized centers. Fetal intervention is now also offered to milder cases within a trial, hypothesizing that this may reduce the occurrence of bronchopulmonary dysplasia in survivors. Postnatal management has been standardized by European high-volume centers for the purpose of this and other trials.
Original languageUndefined/Unknown
Pages (from-to)329-+
JournalClinics in Perinatology
Issue number2
Publication statusPublished - 2009

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