Chest radiography and computed tomography imaging in cystic fibrosis: current challenges and new perspectives

Pierluigi Ciet*, Ronald Booij, Marcel Dijkshoorn, Marcel van Straten, Harm A.W.M. Tiddens

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)
23 Downloads (Pure)

Abstract

Imaging plays a pivotal role in the noninvasive assessment of cystic fibrosis (CF)-related lung damage, which remains the main cause of morbidity and mortality in children with CF. The development of new imaging techniques has significantly changed clinical practice, and advances in therapies have posed diagnostic and monitoring challenges. The authors summarise these challenges and offer new perspectives in the use of imaging for children with CF for both clinicians and radiologists. This article focuses on chest radiography and CT, which are the two main radiologic techniques used in most cystic fibrosis centres. Advantages and disadvantages of radiography and CT for imaging in CF are described, with attention to new developments in these techniques, such as the use of artificial intelligence (AI) image analysis strategies to improve the sensitivity of radiography and CT and the introduction of the photon-counting detector CT scanner to increase spatial resolution at no dose expense.

Original languageEnglish
Pages (from-to)649-659
Number of pages11
JournalPediatric Radiology
Volume53
Issue number4
Early online date29 Oct 2022
DOIs
Publication statusPublished - Apr 2023

Bibliographical note

Publisher Copyright: © 2022, The Author(s).

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