Chlamydia trachomatis-infecties in 4 regio's in Nederland: Resultaten van een bevolkingsonderzoek via de GGD en implicaties voor screening

Translated title of the contribution: Chlamydia trachomatis infection in 4 regions in the Netherlands: Results of a population-based study conducted through municipal health services and implications for screening

J. E.A.M. Van Bergen*, H. M. Götz, J. H. Richardus, C. J.P.A. Hoebe, J. Broer, A. J.J. Coenen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

Objective. To determine the prevalence of Chlamydia trachomatis in people aged 15-29 years and the feasibility of screening through municipal health services. Design. Descriptive. Method. In 2002/'03 a home-sampling kit was sent by mail to 21,003 randomly selected people aged 15-29 years in 4 regions. Urine samples were returned by mail and tested by polymerase chain reaction (PCR). Treatment of those who tested positive was done by general practitioners, a clinic of the municipal and public health services or a clinic for sexually transmitted diseases. Prevalence was determined after adjusting for gender, age and residence. Risk factors were identified using uni- and multivariate analysis and results were converted to a total risk score from which the chance of having a C. trachomatis infection could be calculated. Results. Of the 20,495 persons of the study population 10,610 persons responded (52%): 11% sent in a refusal card and 41% sent in urine. The prevalence of C. trachomatis was 2.0% (95% CI: 1.7-2.3); 2.5% (95% CI: 2.0-3.0) in women and 1.5% (95% CI: 1.1-1.9) in men. Of all 165 cases, 91% were treated. Prevalence was lower in rural areas (0.6%; 95% CI: 0.1-1.1) compared to very highly urbanized areas (3.2%; 95% CI: 2.4-4.0). In addition to degree of urbanization, infection was associated with ethnicity, total number of sex partners and symptoms. The resulting prediction model discriminated well. Conclusion. In people aged 15-29 years, 2% were infected with C. trachomatis. The chance of infection was dependent on various risk factors. The prediction model offers opportunities for selective screening.

Translated title of the contributionChlamydia trachomatis infection in 4 regions in the Netherlands: Results of a population-based study conducted through municipal health services and implications for screening
Original languageDutch
Pages (from-to)2167-2174
Number of pages8
JournalNederlands Tijdschrift voor Geneeskunde
Volume149
Issue number39
Publication statusPublished - 24 Sept 2005

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