Clinical and Molecular Characteristics of Extended-Spectrum-beta-Lactamase-Producing Escherichia coli Causing Bacteremia in the Rotterdam Area, Netherlands

Akke Bij; G Peirano; Wil Goessens; ER van der Vorm; Mireille van Westreenen; JDD Pitout

doi:10.1128/AAC.00074-11

Clinical and Molecular Characteristics of Extended-Spectrum-beta-Lactamase-Producing Escherichia coli Causing Bacteremia in the Rotterdam Area, Netherlands

Akke Bij, G Peirano, Wil Goessens, ER van der Vorm, Mireille van Westreenen, JDD Pitout

Medical Microbiology & Infectious Diseases

Research output: Contribution to journal › Article › Academic › peer-review

58 Citations (Scopus)

Abstract

We investigated the clinical and molecular characteristics of bacteremia caused by extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli over a 2-year period (2008 to 2009) in the Rotterdam region (including 1 teaching hospital and 2 community hospitals) of Netherlands. The majority of patients presented with community onset urinary and intra-abdominal infections, with an increase in prevalence during 2009. The majority of E. coli isolates produced CTX-M-15, and 4 sequence types (ST38, ST131, ST405, and ST648) predominated. There were significant differences in clinical and molecular characteristics between the 2 community hospitals.

Original language	Undefined/Unknown
Pages (from-to)	3576-3578
Number of pages	3
Journal	Antimicrobial Agents & Chemotherapy
Volume	55
Issue number	7
DOIs	https://doi.org/10.1128/AAC.00074-11
Publication status	Published - 2011

Research programs

EMC MM-04-28-01

Access to Document

10.1128/AAC.00074-11

http://hdl.handle.net/1765/33378

Cite this

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title = "Clinical and Molecular Characteristics of Extended-Spectrum-beta-Lactamase-Producing Escherichia coli Causing Bacteremia in the Rotterdam Area, Netherlands",

abstract = "We investigated the clinical and molecular characteristics of bacteremia caused by extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli over a 2-year period (2008 to 2009) in the Rotterdam region (including 1 teaching hospital and 2 community hospitals) of Netherlands. The majority of patients presented with community onset urinary and intra-abdominal infections, with an increase in prevalence during 2009. The majority of E. coli isolates produced CTX-M-15, and 4 sequence types (ST38, ST131, ST405, and ST648) predominated. There were significant differences in clinical and molecular characteristics between the 2 community hospitals.",

author = "Akke Bij and G Peirano and Wil Goessens and {van der Vorm}, ER and {van Westreenen}, Mireille and JDD Pitout",

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AU - van der Vorm, ER

AU - van Westreenen, Mireille

AU - Pitout, JDD

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AB - We investigated the clinical and molecular characteristics of bacteremia caused by extended-spectrum-beta-lactamase (ESBL)-producing Escherichia coli over a 2-year period (2008 to 2009) in the Rotterdam region (including 1 teaching hospital and 2 community hospitals) of Netherlands. The majority of patients presented with community onset urinary and intra-abdominal infections, with an increase in prevalence during 2009. The majority of E. coli isolates produced CTX-M-15, and 4 sequence types (ST38, ST131, ST405, and ST648) predominated. There were significant differences in clinical and molecular characteristics between the 2 community hospitals.

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