Clinical decision support for ExtraCorporeal Membrane Oxygenation: Will we fly by wire?

Lara Pladet*, Kim Luijken, Libera Fresiello, Dinis Dos Reis Miranda, Jeannine A. Hermens, Maarten van Smeden, Olaf Cremer, Dirk W. Donker, Christiaan L. Meuwese

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

3 Citations (Scopus)
22 Downloads (Pure)

Abstract

Prognostic modelling techniques have rapidly evolved over the past decade and may greatly benefit patients supported with ExtraCorporeal Membrane Oxygenation (ECMO). Epidemiological and computational physiological approaches aim to provide more accurate predictive assessments of ECMO-related risks and benefits. Implementation of these approaches may produce predictive tools that can improve complex clinical decisions surrounding ECMO allocation and management. This Review describes current applications of prognostic models and elaborates on upcoming directions for their clinical applicability in decision support tools directed at improved allocation and management of ECMO patients. The discussion of these new developments in the field will culminate in a futuristic perspective leaving ourselves and the readers wondering whether we may “fly ECMO by wire” someday.

Original languageEnglish
Pages (from-to)68-81
Number of pages14
JournalPerfusion (United Kingdom)
Volume38
Issue number1_suppl
Early online date20 Apr 2023
DOIs
Publication statusPublished - 2023

Bibliographical note

Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Primary source of funding: Stichting Gezondheidszorg Spaarneland (SGS) Fund, Zilveren Kruis Achmea.

Funding Information:
The authors thank Drs. A. Vleugelers for his contribution to the figures and Mr. M. Pladet, former F16 pilot and Boeing 737/747/777/787 captain for his contribution to the fly-by-wire section. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: Primary source of funding: Stichting Gezondheidszorg Spaarneland (SGS) Fund, Zilveren Kruis Achmea.

Funding Information:
The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: D.W. Donker from the institutional research cooperation of the Cardiovascular and Respiratory physiology group of the University of Twente with Maquet Critical Care AB, Solna, Sweden and Sonion Nederland BV, Hoofddorp, The Netherlands (no personal honoraria received). C. Meuwese received research funding from “Stichting Gezondheidszorg Spaarneland (SGS)” Fund and The Dutch Heart Foundation (Hartstichting). D. dos Reis Miranda has received honoraria for scientific presentations from Maquet Getinge and Xenios. For the remaining authors none were declared.

Publisher Copyright:
© The Author(s) 2023.

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