Clinical practice guideline on diagnosis and treatment of hyponatraemia

G Spasovski, R Vanholder, B Allolio, D Annane, S Ball, D Bichet, G Decaux, W Fenske, Ewout Hoorn, C Ichai, M Joannidis, A Soupart, R. Zietse, M Haller, S van der Veer, W Van Biesen, E Nagler

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266 Citations (Scopus)

Abstract

Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and length of hospital stay in patients presenting with a range of conditions. Despite this, the management of patients remains problematic. The prevalence of hyponatraemia in widely different conditions and the fact that hyponatraemia is managed by clinicians with a broad variety of backgrounds have fostered diverse institution-and speciality-based approaches to diagnosis and treatment. To obtain a common and holistic view, the European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association - European Dialysis and Transplant Association (ERA-EDTA), represented by European Renal Best Practice (ERBP), have developed the Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia as a joint venture of three societies representing specialists with a natural interest in hyponatraemia. In addition to a rigorous approach to methodology and evaluation, we were keen to ensure that the document focused on patient-important outcomes and included utility for clinicians involved in everyday practice.
Original languageUndefined/Unknown
Pages (from-to)1-39
Number of pages39
JournalNephrology Dialysis Transplantation
Volume29
DOIs
Publication statusPublished - 2014

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