TY - JOUR
T1 - Cognition and Educational Achievement in the Toronto Adolescent and Youth Cohort Study
T2 - Rationale, Methods, and Early Data
AU - Quilty, Lena C
AU - Tempelaar, Wanda
AU - TAY Cohort Study Team
AU - Andrade, Brendan F
AU - Kidd, Sean A
AU - Lunsky, Yona
AU - Chen, Sheng
AU - Wang, Wei
AU - Wong, Jimmy K Y
AU - Lau, Chloe
AU - Sedrak, Andrew B
AU - Kelly, Rachel
AU - Sivakumar, Harijah
AU - Jani, Melanie
AU - Ameis, Stephanie H
AU - Cleverley, Kristin
AU - Goldstein, Benjamin I
AU - Felsky, Daniel
AU - Dickie, Erin W
AU - Foussias, George
AU - Kozloff, Nicole
AU - Nikolova, Yuliya S
AU - Polillo, Alexia
AU - Diaconescu, Andreea O
AU - Wheeler, Anne L
AU - Courtney, Darren B
AU - Hawke, Lisa D
AU - Rotenberg, Martin
AU - Voineskos, Aristotle N
N1 - Publisher Copyright:
© 2023 Society of Biological Psychiatry
PY - 2024/3
Y1 - 2024/3
N2 - Background: Both cognition and educational achievement in youths are linked to psychosis risk. One major aim of the Toronto Adolescent and Youth (TAY) Cohort Study is to characterize how cognitive and educational achievement trajectories inform the course of psychosis spectrum symptoms (PSSs), functioning, and suicidality. Here, we describe the protocol for the cognitive and educational data and early baseline data. Methods: The cognitive assessment design is consistent with youth population cohort studies, including the NIH Toolbox, Rey Auditory Verbal Learning Test, Wechsler Matrix Reasoning Task, and Little Man Task. Participants complete an educational achievement questionnaire, and report cards are requested. Completion rates, descriptive data, and differences across PSS status are reported for the first participants (N = 417) ages 11 to 24 years, who were recruited between May 4, 2021, and February 2, 2023. Results: Nearly 84% of the sample completed cognitive testing, and 88.2% completed the educational questionnaire, whereas report cards were collected for only 40.3%. Modifications to workflows were implemented to improve data collection. Participants who met criteria for PSSs demonstrated lower performance than those who did not on numerous key cognitive indices (p < .05) and also had more academic/educational problems. Conclusions: Following youths longitudinally enabled trajectory mapping and prediction based on cognitive and educational performance in relation to PSSs in treatment-seeking youths. Youths with PSSs had lower cognitive performance and worse educational outcomes than youths without PSSs. Results show the feasibility of collecting data on cognitive and educational outcomes in a cohort of youths seeking treatment related to mental illness and substance use.
AB - Background: Both cognition and educational achievement in youths are linked to psychosis risk. One major aim of the Toronto Adolescent and Youth (TAY) Cohort Study is to characterize how cognitive and educational achievement trajectories inform the course of psychosis spectrum symptoms (PSSs), functioning, and suicidality. Here, we describe the protocol for the cognitive and educational data and early baseline data. Methods: The cognitive assessment design is consistent with youth population cohort studies, including the NIH Toolbox, Rey Auditory Verbal Learning Test, Wechsler Matrix Reasoning Task, and Little Man Task. Participants complete an educational achievement questionnaire, and report cards are requested. Completion rates, descriptive data, and differences across PSS status are reported for the first participants (N = 417) ages 11 to 24 years, who were recruited between May 4, 2021, and February 2, 2023. Results: Nearly 84% of the sample completed cognitive testing, and 88.2% completed the educational questionnaire, whereas report cards were collected for only 40.3%. Modifications to workflows were implemented to improve data collection. Participants who met criteria for PSSs demonstrated lower performance than those who did not on numerous key cognitive indices (p < .05) and also had more academic/educational problems. Conclusions: Following youths longitudinally enabled trajectory mapping and prediction based on cognitive and educational performance in relation to PSSs in treatment-seeking youths. Youths with PSSs had lower cognitive performance and worse educational outcomes than youths without PSSs. Results show the feasibility of collecting data on cognitive and educational outcomes in a cohort of youths seeking treatment related to mental illness and substance use.
UR - http://www.scopus.com/inward/record.url?scp=85184036925&partnerID=8YFLogxK
U2 - 10.1016/j.bpsc.2023.10.012
DO - 10.1016/j.bpsc.2023.10.012
M3 - Article
C2 - 37979945
SN - 2451-9022
VL - 9
SP - 265
EP - 274
JO - Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
JF - Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
IS - 3
ER -
