TY - JOUR
T1 - Cognitive disorders in patients with chronic kidney disease
T2 - Approaches to prevention and treatment
AU - Pépin, Marion
AU - Klimkowicz-Mrowiec, Aleksandra
AU - Godefroy, Olivier
AU - the CONNECT (Cognitive Decline in Nephro-Neurology: European Cooperative Target) Action
AU - Delgado, Pilar
AU - Carriazo, Sol
AU - Ferreira, Ana Carina
AU - Golenia, Aleksandra
AU - Malyszko, Jolanta
AU - Grodzicki, Tomasz
AU - Giannakou, Konstantinos
AU - Paolisso, Giuseppe
AU - Barbieri, Michelangela
AU - Garneata, Liliana
AU - Mocanu, Carmen Antonia
AU - Liabeuf, Sophie
AU - Spasovski, Goce
AU - Zoccali, Carmine
AU - Bruchfeld, Annette
AU - Farinha, Ana
AU - Arici, Mustafa
AU - Capasso, Giovambattista
AU - Wiecek, Andrzej
AU - Massy, Ziad A.
AU - Andrade, Alexandre
AU - Bachmann, Maie
AU - Bumblyte, Inga
AU - Covic, Adrian Constantin
AU - Endlich, Nicole
AU - Engvig, Andreas
AU - Fouque, Denis
AU - Franssen, Casper
AU - Frische, Sebastian
AU - Gesualdo, Loreto
AU - Goumenos, Dimitrios
AU - Mani, Laila Yasmin
AU - Marti, Hans Peter
AU - Mayer, Christopher
AU - Nielsen, Rikke
AU - Pešić, Vesna
AU - Rroji, Merita
AU - Sakkas, Giorgos
AU - Stevens, Kate
AU - Vazelov, Evgueniy
AU - Viggiano, Davide
AU - Zacharia, Lefteris
AU - Hoorn, Ewout
AU - Figurek, Andreja
AU - Mattace Raso, Francesco
AU - Blankestijn, Peter
AU - Imenez Silva, Pedro Henrique
N1 - Publisher Copyright:
© 2023 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology.
PY - 2023/9
Y1 - 2023/9
N2 - Background: Cognitive impairment is common in patients with chronic kidney disease (CKD), and early intervention may prevent the progression of this condition. Methods: Here, we review interventions for the complications of CKD (anemia, secondary hyperparathyroidism, metabolic acidosis, harmful effects of dialysis, the accumulation of uremic toxins) and for prevention of vascular events, interventions that may potentially be protective against cognitive impairment. Furthermore, we discuss nonpharmacological and pharmacological methods to prevent cognitive impairment and/or minimize the latter's impact on CKD patients' daily lives. Results: A particular attention on kidney function assessment is suggested during work-up for cognitive impairment. Different approaches are promising to reduce cognitive burden in patients with CKD but the availabe dedicated data are scarce. Conclusions: There is a need for studies assessing the effect of interventions on the cognitive function of patients with CKD.
AB - Background: Cognitive impairment is common in patients with chronic kidney disease (CKD), and early intervention may prevent the progression of this condition. Methods: Here, we review interventions for the complications of CKD (anemia, secondary hyperparathyroidism, metabolic acidosis, harmful effects of dialysis, the accumulation of uremic toxins) and for prevention of vascular events, interventions that may potentially be protective against cognitive impairment. Furthermore, we discuss nonpharmacological and pharmacological methods to prevent cognitive impairment and/or minimize the latter's impact on CKD patients' daily lives. Results: A particular attention on kidney function assessment is suggested during work-up for cognitive impairment. Different approaches are promising to reduce cognitive burden in patients with CKD but the availabe dedicated data are scarce. Conclusions: There is a need for studies assessing the effect of interventions on the cognitive function of patients with CKD.
UR - http://www.scopus.com/inward/record.url?scp=85163668939&partnerID=8YFLogxK
U2 - 10.1111/ene.15928
DO - 10.1111/ene.15928
M3 - Review article
C2 - 37326125
AN - SCOPUS:85163668939
SN - 1351-5101
VL - 30
SP - 2899
EP - 2911
JO - European Journal of Neurology
JF - European Journal of Neurology
IS - 9
ER -