Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment

Marion Pépin*, Ana Carina Ferreira, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) , Mustafa Arici, Maie Bachman, Michelangela Barbieri, Inga Arune Bumblyte, Sol Carriazo, Pilar Delgado, Liliana Garneata, Konstantinos Giannakou, Olivier Godefroy, Tomasz Grodzicki, Aleksandra Klimkowicz-Mrowiec, Justina Kurganaite, Sophie Liabeuf, Carmen Antonia Mocanu, Giuseppe Paolisso, Goce Spasovski, Evgueniy Stefanov VazelovDavide Viggiano, Carmine Zoccali, Ziad A. Massy, Andrzej WieRcek

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)
33 Downloads (Pure)


Neurocognitive disorders are frequent among chronic kidney disease (CKD) patients. Identifying and characterizing cognitive impairment (CI) can help to assess the ability of adherence to CKD risk reduction strategy, identify potentially reversible causes of cognitive decline, modify pharmacotherapy, educate the patient and caregiver and provide appropriate patient and caregiver support. Numerous factors are associated with the development and progression of CI in CKD patients and various conditions can influence the results of cognitive assessment in these patients. Here we review clinical warning signs that should lead to cognitive screening; conditions frequent in CKD at risk to interfere with cognitive testing or performance, including specificities of cognitive assessment in dialysis patients or after kidney transplantation; and available tests for screening and observed cognitive patterns in CKD patients.

Original languageEnglish
Pages (from-to)II23-II32
JournalNephrology Dialysis Transplantation
Early online date31 Oct 2021
Publication statusPublished - Jan 2022

Bibliographical note

Funding Information:
This article is published as part of a supplement financially supported by the COST Action CA19127-Cognitive Decline in Nephro-Neurology: European Cooperative Target (CONNECT).

Publisher Copyright:
© The Author(s) 2021. Published by Oxford University Press on behalf of ERA.


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