Mass spectrometry-based techniques can be applied to investigate collagen with respect to identification, quantification, supramolecular organization, and various post-translational modifications. The continuous interest in collagen research has led to a shift from techniques to analyze the physical characteristics of collagen to methods to study collagen abundance and modifications. In this review, we illustrate the potential of mass spectrometry for in-depth analyses of collagen.
|Number of pages||27|
|Journal||Mass Spectrometry Reviews|
|Publication status||Published - 1 Jul 2020|
Bibliographical noteFunding Information:
The authors gratefully acknowledge the Netherlands Organization for Scientific Research NWO (Domain Applied and Engineering Sciences; Perspectiefprogramma P12-04, project 13541) and the Dutch Biomarker Development Center (BDC; http://www.biomarkerdevelopmentcenter.nl/) for support of this work.
© 2019 John Wiley & Sons Ltd.