TY - JOUR
T1 - Combined liver-kidney transplantation with delayed kidney implantation
T2 - A case report
AU - Bouari, Sarah
AU - Polak, Wojciech G.
AU - van de Wetering, Jacqueline
AU - Metselaar, Herold J.
AU - IJzermans, Jan N.M.
AU - Minnee, Robert C.
N1 - Funding:
This research did not receive any specific grant from funding
agencies in the public, commercial, or not-for-profit sectors.
Publisher Copyright:
© 2023 The Author(s)
PY - 2023/5
Y1 - 2023/5
N2 - Introduction: In rare cases, patients require a combined liver-kidney transplant. However, the peri- and postoperative care of liver transplant recipients differs from kidney transplant recipients, which can lead to conflicts of interest. In the case of poor coagulation status and/or instable hemodynamics of the patient, liver transplantation, followed by delayed kidney transplantation can lead to better postoperative recovery. Presentation of case: In our case report, we present a 48-year old man with Alagille syndrome and IgA nephropathy with bilirubin-associated acute kidney injury, causing him to develop both end-stage liver and kidney disease. He underwent a combined liver-kidney transplant as the first patient in the Netherlands, in which the donor kidney was transplanted one day after the liver transplantation. One-year post-transplant patient is in good clinical condition, with normal liver function and an eGFR of 57 ml/min. Conclusion: Combined liver-kidney transplantation with delayed kidney implantation in a medical center with no previous experience with this technique is feasible and safe. This could be better for both the patient and the kidney graft.
AB - Introduction: In rare cases, patients require a combined liver-kidney transplant. However, the peri- and postoperative care of liver transplant recipients differs from kidney transplant recipients, which can lead to conflicts of interest. In the case of poor coagulation status and/or instable hemodynamics of the patient, liver transplantation, followed by delayed kidney transplantation can lead to better postoperative recovery. Presentation of case: In our case report, we present a 48-year old man with Alagille syndrome and IgA nephropathy with bilirubin-associated acute kidney injury, causing him to develop both end-stage liver and kidney disease. He underwent a combined liver-kidney transplant as the first patient in the Netherlands, in which the donor kidney was transplanted one day after the liver transplantation. One-year post-transplant patient is in good clinical condition, with normal liver function and an eGFR of 57 ml/min. Conclusion: Combined liver-kidney transplantation with delayed kidney implantation in a medical center with no previous experience with this technique is feasible and safe. This could be better for both the patient and the kidney graft.
UR - http://www.scopus.com/inward/record.url?scp=85156158849&partnerID=8YFLogxK
U2 - 10.1016/j.ijscr.2023.108276
DO - 10.1016/j.ijscr.2023.108276
M3 - Article
C2 - 37150159
AN - SCOPUS:85156158849
SN - 2210-2612
VL - 106
JO - International Journal of Surgery Case Reports
JF - International Journal of Surgery Case Reports
M1 - 108276
ER -