Common genetic determinants of vitamin D insufficiency: A genome-wide association study

the SUNLIGHT Consortium

doi:10.1097/OGX.0b013e318216b03d

Common genetic determinants of vitamin D insufficiency: A genome-wide association study

the SUNLIGHT Consortium

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Abstract

Environmental disorders associated with vitamin D deficiency include musculoskeletal disorders (childhood rickets, osteomalacia, and fractures), and may include extraskeletal disorders (diabetes, cardiovascular disease, risk of falls, and cancer). There is high interindividual variability in the occurrence of both musculoskeletal and extraskeletal disorders. Previous twin and family studies suggested that genetic factors play a significant role in this variability. Little data exist on the possible effects of common genetic variation on vitamin D status; the available studies have been small and only small numbers of variants were examined. [...]

Original language	English
Pages (from-to)	91-93
Number of pages	3
Journal	Obstetrical and Gynecological Survey
Volume	66
Issue number	2
DOIs	https://doi.org/10.1097/OGX.0b013e318216b03d
Publication status	Published - Feb 2011

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10.1097/OGX.0b013e318216b03d

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title = "Common genetic determinants of vitamin D insufficiency: A genome-wide association study",

abstract = "Environmental disorders associated with vitamin D deficiency include musculoskeletal disorders (childhood rickets, osteomalacia, and fractures), and may include extraskeletal disorders (diabetes, cardiovascular disease, risk of falls, and cancer). There is high interindividual variability in the occurrence of both musculoskeletal and extraskeletal disorders. Previous twin and family studies suggested that genetic factors play a significant role in this variability. Little data exist on the possible effects of common genetic variation on vitamin D status; the available studies have been small and only small numbers of variants were examined. [...]",

author = "{the SUNLIGHT Consortium} and Wang, {Thomas J.} and Feng Zhang and Richards, {J. Brent} and Bryan Kestenbaum and {Van Meurs}, {Joyce B.} and Diane Berry and Kiel, {Douglas P.} and Streeten, {Elizabeth A.} and Claes Ohlsson and Koller, {Daniel L.} and Leena Peltonen and Cooper, {Jason D.} and O'Reilly, {Paul F.} and Houston, {Denise K.} and Glazer, {Nicole L.} and Liesbeth Vandenput and Munro Peacock and Julia Shi and Fernando Rivadeneira and McCarthy, {Mark I.} and Pouta Anneli and {De Boer}, {Ian H.} and Massimo Mangino and Bernet Kato and Smyth, {Deborah J.} and Booth, {Sarah L.} and Jacques, {Paul F.} and Burke, {Greg L.} and Mark Goodarzi and Cheung, {Ching Lung} and Myles Wolf and Kenneth Rice and David Goltzman and Nick Hidiroglou and Martin Ladouceur and Wareham, {Nicholas J.} and Hocking, {Lynne J.} and Deborah Hart and Arden, {Nigel K.} and Cyrus Cooper and Suneil Malik and Fraser, {William D.} and Hartikainen, {Anna Liisa} and Guangju Zhai and MacDonald, {Helen M.} and Yongmei Liu and Albert Hofman and Uitterlinden, {Andre G.} and Florez, {Jose C.} and Josee Dupuis",

year = "2011",

month = feb,

doi = "10.1097/OGX.0b013e318216b03d",

language = "English",

volume = "66",

pages = "91--93",

journal = "Obstetrical and Gynecological Survey",

issn = "0029-7828",

publisher = "Lippincott Williams & Wilkins",

number = "2",

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T1 - Common genetic determinants of vitamin D insufficiency

T2 - A genome-wide association study

AU - the SUNLIGHT Consortium

AU - Wang, Thomas J.

AU - Zhang, Feng

AU - Richards, J. Brent

AU - Kestenbaum, Bryan

AU - Van Meurs, Joyce B.

AU - Berry, Diane

AU - Kiel, Douglas P.

AU - Streeten, Elizabeth A.

AU - Ohlsson, Claes

AU - Koller, Daniel L.

AU - Peltonen, Leena

AU - Cooper, Jason D.

AU - O'Reilly, Paul F.

AU - Houston, Denise K.

AU - Glazer, Nicole L.

AU - Vandenput, Liesbeth

AU - Peacock, Munro

AU - Shi, Julia

AU - Rivadeneira, Fernando

AU - McCarthy, Mark I.

AU - Anneli, Pouta

AU - De Boer, Ian H.

AU - Mangino, Massimo

AU - Kato, Bernet

AU - Smyth, Deborah J.

AU - Booth, Sarah L.

AU - Jacques, Paul F.

AU - Burke, Greg L.

AU - Goodarzi, Mark

AU - Cheung, Ching Lung

AU - Wolf, Myles

AU - Rice, Kenneth

AU - Goltzman, David

AU - Hidiroglou, Nick

AU - Ladouceur, Martin

AU - Wareham, Nicholas J.

AU - Hocking, Lynne J.

AU - Hart, Deborah

AU - Arden, Nigel K.

AU - Cooper, Cyrus

AU - Malik, Suneil

AU - Fraser, William D.

AU - Hartikainen, Anna Liisa

AU - Zhai, Guangju

AU - MacDonald, Helen M.

AU - Liu, Yongmei

AU - Hofman, Albert

AU - Uitterlinden, Andre G.

AU - Florez, Jose C.

AU - Dupuis, Josee

PY - 2011/2

Y1 - 2011/2

N2 - Environmental disorders associated with vitamin D deficiency include musculoskeletal disorders (childhood rickets, osteomalacia, and fractures), and may include extraskeletal disorders (diabetes, cardiovascular disease, risk of falls, and cancer). There is high interindividual variability in the occurrence of both musculoskeletal and extraskeletal disorders. Previous twin and family studies suggested that genetic factors play a significant role in this variability. Little data exist on the possible effects of common genetic variation on vitamin D status; the available studies have been small and only small numbers of variants were examined. [...]

AB - Environmental disorders associated with vitamin D deficiency include musculoskeletal disorders (childhood rickets, osteomalacia, and fractures), and may include extraskeletal disorders (diabetes, cardiovascular disease, risk of falls, and cancer). There is high interindividual variability in the occurrence of both musculoskeletal and extraskeletal disorders. Previous twin and family studies suggested that genetic factors play a significant role in this variability. Little data exist on the possible effects of common genetic variation on vitamin D status; the available studies have been small and only small numbers of variants were examined. [...]

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U2 - 10.1097/OGX.0b013e318216b03d

DO - 10.1097/OGX.0b013e318216b03d

M3 - Comment/Letter to the editor

AN - SCOPUS:79958117230

SN - 0029-7828

VL - 66

SP - 91

EP - 93

JO - Obstetrical and Gynecological Survey

JF - Obstetrical and Gynecological Survey

IS - 2

ER -

Common genetic determinants of vitamin D insufficiency: A genome-wide association study

Abstract

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