Comparison of plaque prolapse in consecutive patients treated with Xience V and Taxus Liberte stents

ZJ Shen, S Brugaletta, Hector Garcia Garcia, Jurgen Ligthart, Josep Gomez Lara, Roberto Diletti, Giovanna Sarno, Karen Witberg, PWJC (Patrick) Serruys

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The purpose of this article is to investigate the prevalence of plaque prolapse (PP) after Xience V and Taxus Liberte stent implantation. During the study period 2006-2007, 200 consecutive patients underwent coronary revascularization for de novo lesions and received an intravascular ultrasound (IVUS) post-stenting evaluation, (n = 124 patients with Taxus Liberte and n = 76 with Xience V) (227 stent segments). Cross-sectional and longitudinal 3D IVUS images were analyzed in a blind fashion, evaluating the prevalence of PP and calculating its depth and angle. The angulation degree of the coronary artery at the lesion site pre-stent implantation was also evaluated by angiography. The prevalence of PP was 23.9% in Xience V versus 38.1% in Taxus Liberte (P = 0.025). The depth and angle of PP were greater in Taxus Liberte stent than Xience V stent (0.4 +/- A 0.1 mm versus 0.5 +/- A 0.2 mm, P = 0.004; and 32.0 +/- A 8.9A degrees versus 44.6 +/- A 27.6A degrees, P = 0.044, respectively). The angulation degree of the coronary artery at the lesion site was higher in presence of plaque prolapse than in its absence (48.2 +/- A 29.3A degrees vs. 38.2 +/- A 28.1A degrees, P = 0.013). By multivariate analysis, stent type was independently associated with incidence of plaque prolapse. Xience V stent has less plaque prolapse than Taxus Liberte stent. Stent design may play a role in the prevalence of plaque prolapse.
Original languageUndefined/Unknown
Pages (from-to)23-31
Number of pages9
JournalInternational Journal of Cardiovascular Imaging
Issue number1
Publication statusPublished - 2012

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