TY - JOUR
T1 - Complete genome analysis of hepatitis C virus subtypes 6t and 6u
AU - Noppornpanth, S (Suwanna)
AU - Poovorawan, Y
AU - Lien, TX
AU - Smits, Saskia
AU - Osterhaus, Ab
AU - Haagmans, Bart
PY - 2008
Y1 - 2008
N2 - Hepatitis C virus (HCV) genomes exhibit high nucleotide sequence diversity. In this study, we performed complete genome sequence analysis of 11 HCV genotype 6 samples from Vietnam and Thailand, We identified nine HCV complete genomes belonging to subtypes 6a. (D9), 6e (D42 and D88), 6f (TH52), 6i (TH24), 61 (D33), 6n (TH22 and TH31) and 6o (D85). Phylogenetic analysis of the core/E1 and NS5B regions from unclassified genotype 6 isolates from Asian immigrants in Canada revealed that two other viruses (D49 and D83) could be classified as novel candidates of HCV subtypes 6t and 6u.
AB - Hepatitis C virus (HCV) genomes exhibit high nucleotide sequence diversity. In this study, we performed complete genome sequence analysis of 11 HCV genotype 6 samples from Vietnam and Thailand, We identified nine HCV complete genomes belonging to subtypes 6a. (D9), 6e (D42 and D88), 6f (TH52), 6i (TH24), 61 (D33), 6n (TH22 and TH31) and 6o (D85). Phylogenetic analysis of the core/E1 and NS5B regions from unclassified genotype 6 isolates from Asian immigrants in Canada revealed that two other viruses (D49 and D83) could be classified as novel candidates of HCV subtypes 6t and 6u.
U2 - 10.1099/vir.0.83593-0
DO - 10.1099/vir.0.83593-0
M3 - Article
SN - 0022-1317
VL - 89
SP - 1276
EP - 1281
JO - Journal of General Virology
JF - Journal of General Virology
ER -
