Complications due to transfusion-related acute lung injury: 81-84

W. Droog; S. W. Van Thiel; S. J.Sleeswijk Visser; J. P.T. Rhemrev

doi:10.1097/AOG.0b013e318193c059

Complications due to transfusion-related acute lung injury: 81-84

W. Droog, S. W. Van Thiel, S. J.Sleeswijk Visser, J. P.T. Rhemrev^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

Abstract

Background:

Transfusion-related acute lung injury is an underdiagnosed and potentially lethal complication of blood transfusion.

Case:

A patient underwent surgery because of an ectopic pregnancy. During surgery, blood products were administered and within minutes she developed pulmonary edema and hypotension. Treatment included mechanical ventilation, intravenous fluids, antihistamines, inotropic agents, cortisol, and diuretics. It took 4 days for the pulmonary edema to resolve and the patient to recover. Analysis of the donor plasma revealed human leukocyte antigen antibodies against an antigen of the patient.

Conclusion:

Although transfusion-related acute lung injury is usually self-limiting and most patients will recover spontaneously, the estimated mortality rate of 5-25% warrants prompt identification and adequate action.

Original language	English
Pages (from-to)	560-563
Number of pages	4
Journal	Obstetrics and Gynecology
Volume	113
Issue number	2 PART 2
DOIs	https://doi.org/10.1097/AOG.0b013e318193c059
Publication status	Published - Feb 2009
Externally published	Yes

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10.1097/AOG.0b013e318193c059

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title = "Complications due to transfusion-related acute lung injury: 81-84",

abstract = "Background: Transfusion-related acute lung injury is an underdiagnosed and potentially lethal complication of blood transfusion. Case: A patient underwent surgery because of an ectopic pregnancy. During surgery, blood products were administered and within minutes she developed pulmonary edema and hypotension. Treatment included mechanical ventilation, intravenous fluids, antihistamines, inotropic agents, cortisol, and diuretics. It took 4 days for the pulmonary edema to resolve and the patient to recover. Analysis of the donor plasma revealed human leukocyte antigen antibodies against an antigen of the patient. Conclusion: Although transfusion-related acute lung injury is usually self-limiting and most patients will recover spontaneously, the estimated mortality rate of 5-25% warrants prompt identification and adequate action.",

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AU - Droog, W.

AU - Van Thiel, S. W.

AU - Visser, S. J.Sleeswijk

AU - Rhemrev, J. P.T.

PY - 2009/2

Y1 - 2009/2

N2 - Background: Transfusion-related acute lung injury is an underdiagnosed and potentially lethal complication of blood transfusion. Case: A patient underwent surgery because of an ectopic pregnancy. During surgery, blood products were administered and within minutes she developed pulmonary edema and hypotension. Treatment included mechanical ventilation, intravenous fluids, antihistamines, inotropic agents, cortisol, and diuretics. It took 4 days for the pulmonary edema to resolve and the patient to recover. Analysis of the donor plasma revealed human leukocyte antigen antibodies against an antigen of the patient. Conclusion: Although transfusion-related acute lung injury is usually self-limiting and most patients will recover spontaneously, the estimated mortality rate of 5-25% warrants prompt identification and adequate action.

AB - Background: Transfusion-related acute lung injury is an underdiagnosed and potentially lethal complication of blood transfusion. Case: A patient underwent surgery because of an ectopic pregnancy. During surgery, blood products were administered and within minutes she developed pulmonary edema and hypotension. Treatment included mechanical ventilation, intravenous fluids, antihistamines, inotropic agents, cortisol, and diuretics. It took 4 days for the pulmonary edema to resolve and the patient to recover. Analysis of the donor plasma revealed human leukocyte antigen antibodies against an antigen of the patient. Conclusion: Although transfusion-related acute lung injury is usually self-limiting and most patients will recover spontaneously, the estimated mortality rate of 5-25% warrants prompt identification and adequate action.

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AN - SCOPUS:60549087377

SN - 0029-7844

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JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

IS - 2 PART 2

ER -

Complications due to transfusion-related acute lung injury: 81-84

Abstract

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