Computed Tomography Coronary Angiography in Patients With Acute Myocardial Infarction Without Significant Coronary Stenosis

A Aldrovandi; F. Cademartiri; D Arduini; D Lina; F Ugo; E Maffei; A (Alberto) Menozzi; C Martini; A Palumbo; F Bontardelli; T Gherli; L Ruffini; D Ardissino

doi:10.1161/CIRCULATIONAHA.112.117598

Computed Tomography Coronary Angiography in Patients With Acute Myocardial Infarction Without Significant Coronary Stenosis

A Aldrovandi, F. Cademartiri, D Arduini, D Lina, F Ugo, E Maffei, A (Alberto) Menozzi, C Martini, A Palumbo, F Bontardelli, T Gherli, L Ruffini, D Ardissino

Research output: Contribution to journal › Article › Academic › peer-review

50 Citations (Scopus)

Abstract

Background-It is known that a significant number of patients experiencing an acute myocardial infarction have normal coronary arteries or nonsignificant coronary disease at coronary angiography (CA). Computed tomography coronary angiography (CTCA) can identify the presence of plaques, even in the absence of significant coronary stenosis. This study evaluated the role of 64-slice CTCA in detecting and characterizing coronary atherosclerosis in these patients. Methods and Results-Consecutive patients with documented acute myocardial infarction but without significant coronary stenosis at CA underwent late gadolinium-enhanced magnetic resonance and CTCA. Only the 50 patients with an area of myocardial infarction identified by late gadolinium-enhanced magnetic resonance were included in the study. All of the coronary segments were assessed for the presence of plaques. CTCA identified 101 plaques against the 41 identified by CA: 61 (60.4%) located in inf Conclusions-CTCA detects coronary plaques in nonstenotic coronary arteries that are underestimated by CA, and identifies a different distribution of plaque types in IRAs and non-IRAs. It may therefore be valuable for diagnosing coronary atherosclerosis in acute myocardial infarction patients without significant coronary stenosis. (Circulation. 2012;126:3000-3007.)

Original language	Undefined/Unknown
Pages (from-to)	3000-3007
Number of pages	8
Journal	Circulation
Volume	126
Issue number	25
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.112.117598
Publication status	Published - 2012

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EMC NIHES-03-30-01

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10.1161/CIRCULATIONAHA.112.117598

http://hdl.handle.net/1765/61441

Cite this

Aldrovandi, A., Cademartiri, F., Arduini, D., Lina, D., Ugo, F., Maffei, E., Menozzi, A., Martini, C., Palumbo, A., Bontardelli, F., Gherli, T., Ruffini, L., & Ardissino, D. (2012). Computed Tomography Coronary Angiography in Patients With Acute Myocardial Infarction Without Significant Coronary Stenosis. Circulation, 126(25), 3000-3007. https://doi.org/10.1161/CIRCULATIONAHA.112.117598

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title = "Computed Tomography Coronary Angiography in Patients With Acute Myocardial Infarction Without Significant Coronary Stenosis",

abstract = "Background-It is known that a significant number of patients experiencing an acute myocardial infarction have normal coronary arteries or nonsignificant coronary disease at coronary angiography (CA). Computed tomography coronary angiography (CTCA) can identify the presence of plaques, even in the absence of significant coronary stenosis. This study evaluated the role of 64-slice CTCA in detecting and characterizing coronary atherosclerosis in these patients. Methods and Results-Consecutive patients with documented acute myocardial infarction but without significant coronary stenosis at CA underwent late gadolinium-enhanced magnetic resonance and CTCA. Only the 50 patients with an area of myocardial infarction identified by late gadolinium-enhanced magnetic resonance were included in the study. All of the coronary segments were assessed for the presence of plaques. CTCA identified 101 plaques against the 41 identified by CA: 61 (60.4%) located in inf Conclusions-CTCA detects coronary plaques in nonstenotic coronary arteries that are underestimated by CA, and identifies a different distribution of plaque types in IRAs and non-IRAs. It may therefore be valuable for diagnosing coronary atherosclerosis in acute myocardial infarction patients without significant coronary stenosis. (Circulation. 2012;126:3000-3007.)",

author = "A Aldrovandi and F. Cademartiri and D Arduini and D Lina and F Ugo and E Maffei and Menozzi, {A (Alberto)} and C Martini and A Palumbo and F Bontardelli and T Gherli and L Ruffini and D Ardissino",

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Aldrovandi, A, Cademartiri, F, Arduini, D, Lina, D, Ugo, F, Maffei, E, Menozzi, A, Martini, C, Palumbo, A, Bontardelli, F, Gherli, T, Ruffini, L & Ardissino, D 2012, 'Computed Tomography Coronary Angiography in Patients With Acute Myocardial Infarction Without Significant Coronary Stenosis', Circulation, vol. 126, no. 25, pp. 3000-3007. https://doi.org/10.1161/CIRCULATIONAHA.112.117598

TY - JOUR

T1 - Computed Tomography Coronary Angiography in Patients With Acute Myocardial Infarction Without Significant Coronary Stenosis

AU - Aldrovandi, A

AU - Cademartiri, F.

AU - Arduini, D

AU - Lina, D

AU - Ugo, F

AU - Maffei, E

AU - Menozzi, A (Alberto)

AU - Martini, C

AU - Palumbo, A

AU - Bontardelli, F

AU - Gherli, T

AU - Ruffini, L

AU - Ardissino, D

PY - 2012

Y1 - 2012

N2 - Background-It is known that a significant number of patients experiencing an acute myocardial infarction have normal coronary arteries or nonsignificant coronary disease at coronary angiography (CA). Computed tomography coronary angiography (CTCA) can identify the presence of plaques, even in the absence of significant coronary stenosis. This study evaluated the role of 64-slice CTCA in detecting and characterizing coronary atherosclerosis in these patients. Methods and Results-Consecutive patients with documented acute myocardial infarction but without significant coronary stenosis at CA underwent late gadolinium-enhanced magnetic resonance and CTCA. Only the 50 patients with an area of myocardial infarction identified by late gadolinium-enhanced magnetic resonance were included in the study. All of the coronary segments were assessed for the presence of plaques. CTCA identified 101 plaques against the 41 identified by CA: 61 (60.4%) located in inf Conclusions-CTCA detects coronary plaques in nonstenotic coronary arteries that are underestimated by CA, and identifies a different distribution of plaque types in IRAs and non-IRAs. It may therefore be valuable for diagnosing coronary atherosclerosis in acute myocardial infarction patients without significant coronary stenosis. (Circulation. 2012;126:3000-3007.)

AB - Background-It is known that a significant number of patients experiencing an acute myocardial infarction have normal coronary arteries or nonsignificant coronary disease at coronary angiography (CA). Computed tomography coronary angiography (CTCA) can identify the presence of plaques, even in the absence of significant coronary stenosis. This study evaluated the role of 64-slice CTCA in detecting and characterizing coronary atherosclerosis in these patients. Methods and Results-Consecutive patients with documented acute myocardial infarction but without significant coronary stenosis at CA underwent late gadolinium-enhanced magnetic resonance and CTCA. Only the 50 patients with an area of myocardial infarction identified by late gadolinium-enhanced magnetic resonance were included in the study. All of the coronary segments were assessed for the presence of plaques. CTCA identified 101 plaques against the 41 identified by CA: 61 (60.4%) located in inf Conclusions-CTCA detects coronary plaques in nonstenotic coronary arteries that are underestimated by CA, and identifies a different distribution of plaque types in IRAs and non-IRAs. It may therefore be valuable for diagnosing coronary atherosclerosis in acute myocardial infarction patients without significant coronary stenosis. (Circulation. 2012;126:3000-3007.)

U2 - 10.1161/CIRCULATIONAHA.112.117598

DO - 10.1161/CIRCULATIONAHA.112.117598

M3 - Article

C2 - 23168414

SN - 0009-7322

VL - 126

SP - 3000

EP - 3007

JO - Circulation

JF - Circulation

IS - 25

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