Abstract
A congenital diaphragmatic hernia (CDH) is a rare birth defect characterised by
incomplete closure of the diaphragm. After birth, CDH is associated with significant
neonatal morbidity and mortality due to a combination of pulmonary hypoplasia,
pulmonary hypertension, and cardiac dysfunction. Despite improvements in clinical
care, around 30% of these infants do not survive. The research projects reported
in this thesis provide a critical appraisal of important aspects of perinatal care for
infants with CDH.
incomplete closure of the diaphragm. After birth, CDH is associated with significant
neonatal morbidity and mortality due to a combination of pulmonary hypoplasia,
pulmonary hypertension, and cardiac dysfunction. Despite improvements in clinical
care, around 30% of these infants do not survive. The research projects reported
in this thesis provide a critical appraisal of important aspects of perinatal care for
infants with CDH.
| Original language | English |
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| Awarding Institution |
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| Supervisors/Advisors |
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| Award date | 7 Nov 2023 |
| Place of Publication | Rotterdam |
| Print ISBNs | 978-94-6361-905-9 |
| Publication status | Published - 7 Nov 2023 |
Bibliographical note
Financial support by ChipSoft, Concord Neonatal, the Department of Obstetrics and Gynaecology– Erasmus MC University Medical Center, and the Erasmus University Rotterdam for the printing
of this thesis is gratefully acknowledged.