Abstract
Traumatic brain injury and generalized convulsive status epilepticus (GCSE) are conditions that require aggressive management. Barbiturates are used to lower intracranial pressure or to stop epileptiform activity, with the aim being to improve neurological outcome. Dosing of barbiturates is usually guided by the extent of induced burst-suppression pattern on the electroencephalogram (EEG). Dosing beyond the point of burst suppression may increase the risk for complications without offering further therapeutic benefit. For this reason, careful monitoring of EEG parameters is mandatory. A prospective study was conducted to evaluate the usefulness of the bispectral index suppression ratio for monitoring barbiturate coma.
Original language | English |
---|---|
Article number | R108 |
Number of pages | 7 |
Journal | Critical Care |
Volume | 11 |
Issue number | 5 |
DOIs | |
Publication status | Published - 27 Sept 2007 |
Research programs
- EMC MGC-02-53-01-A
- EMC MM-04-44-02