Continuous noninvasive monitoring of barbiturate coma in critically ill children using the BispectralTM index monitor

Sandra A. Prins, Matthijs de Hoog, Joleen H. Blok, Dick Tibboel*, Gerard H. Visser

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Abstract

Traumatic brain injury and generalized convulsive status epilepticus (GCSE) are conditions that require aggressive management. Barbiturates are used to lower intracranial pressure or to stop epileptiform activity, with the aim being to improve neurological outcome. Dosing of barbiturates is usually guided by the extent of induced burst-suppression pattern on the electroencephalogram (EEG). Dosing beyond the point of burst suppression may increase the risk for complications without offering further therapeutic benefit. For this reason, careful monitoring of EEG parameters is mandatory. A prospective study was conducted to evaluate the usefulness of the bispectral index suppression ratio for monitoring barbiturate coma.
Original languageEnglish
Article numberR108
Number of pages7
JournalCritical Care
Volume11
Issue number5
DOIs
Publication statusPublished - 27 Sept 2007

Research programs

  • EMC MGC-02-53-01-A
  • EMC MM-04-44-02

Fingerprint

Dive into the research topics of 'Continuous noninvasive monitoring of barbiturate coma in critically ill children using the BispectralTM index monitor'. Together they form a unique fingerprint.

Cite this