Continuous Versus Discontinuous Distraction: Evaluation of Bone Regenerate Following Various Rhythms of Distraction

Purpose: To investigate continuous distraction osteogenesis (DO) of the nasal bones in a rabbit model, mid to compare data from this continuous DO studs, with data from a previously conducted discontinuous DO study. In scores addition, radiographic and ultrasonographic bone-fill scores were determined to investigate whether these provided reliable predictive value for the amount of new bone formation in the distraction area. Materials and Methods: Skeletally mature female New Zealand White rabbits were subjected to distraction of the nasal bones. A Custom-made continuous distractor was used to perform automatic non-stop distraction. Bone data were obtained from radiography, ultrasonography, and microcomputed tomography. Data from this experiment were compared with data from a previous study on discontinuous distraction rhythms. Results: Ultrasonographic bone-fill scores correlated significantly to actual bone volume in contrast to radiographic bone-fill scores. Bone volume was significantly higher in the continuous DO group compared with the discontinuous DO groups. Conclusion: Continuous distraction resulted in accelerated osteogenesis compared with discontinuous distraction. Furthermore, bone-fill scores based on ultrasonography showed a significant correlation with actual bone volumes. (C) 2009 American Association of Oral and Maxillofacial Surgeons