Corticale blindheid tijdens behandeling met ciclosporine

L. T. Vlasveld; J. J. Cornelissen; P. L.I. Dellemijn; M. V. Joosse; M. J. Van Den Bent

Corticale blindheid tijdens behandeling met ciclosporine

Translated title of the contribution: Cortical blindness during cyclosporin treatment

L. T. Vlasveld^*
, J. J. Cornelissen
, P. L.I. Dellemijn
, M. V. Joosse
, M. J. Van Den Bent

^*Corresponding author for this work

Daniel den Hoed Clinic

Research output: Contribution to journal › Short survey › Academic › peer-review

2 Citations (Scopus)

Abstract

A 40-year-old man developed cortical blindness during cyclosporin treatment shortly after an allogeneic bone marrow transplantation for chronic myeloid leukaemia. At that time the patient had a therapeutic cyclosporin blood level (226 ng/ml), but a low serum magnesium level and a marginally decreased serum cholesterol level. In addition the patient had hypertension, headache and paraesthesia in the oral, palmar and plantar areas. Vision was fully recovered after discontinuation of the cyclosporin treatment and correction of the hypomagnesaemia. Eighteen cases of cortical blindness during cyclosporin treatment are now known in the literature. Hypomagnesaemia appears to be implicated in the pathogenesis.

Translated title of the contribution	Cortical blindness during cyclosporin treatment
Original language	Dutch
Pages (from-to)	2057-2061
Number of pages	5
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	138
Issue number	41
Publication status	Published - 14 Oct 1994

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@article{44c8f6dcc2a74c739e3480fd805280d3,

title = "Corticale blindheid tijdens behandeling met ciclosporine",

abstract = "A 40-year-old man developed cortical blindness during cyclosporin treatment shortly after an allogeneic bone marrow transplantation for chronic myeloid leukaemia. At that time the patient had a therapeutic cyclosporin blood level (226 ng/ml), but a low serum magnesium level and a marginally decreased serum cholesterol level. In addition the patient had hypertension, headache and paraesthesia in the oral, palmar and plantar areas. Vision was fully recovered after discontinuation of the cyclosporin treatment and correction of the hypomagnesaemia. Eighteen cases of cortical blindness during cyclosporin treatment are now known in the literature. Hypomagnesaemia appears to be implicated in the pathogenesis.",

author = "Vlasveld, \{L. T.\} and Cornelissen, \{J. J.\} and Dellemijn, \{P. L.I.\} and Joosse, \{M. V.\} and \{Van Den Bent\}, \{M. J.\}",

year = "1994",

month = oct,

day = "14",

language = "Dutch",

volume = "138",

pages = "2057--2061",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "Vereniging Nederlands Tijdschrift voor Geneeskunde",

number = "41",

}

TY - JOUR

T1 - Corticale blindheid tijdens behandeling met ciclosporine

AU - Vlasveld, L. T.

AU - Cornelissen, J. J.

AU - Dellemijn, P. L.I.

AU - Joosse, M. V.

AU - Van Den Bent, M. J.

PY - 1994/10/14

Y1 - 1994/10/14

N2 - A 40-year-old man developed cortical blindness during cyclosporin treatment shortly after an allogeneic bone marrow transplantation for chronic myeloid leukaemia. At that time the patient had a therapeutic cyclosporin blood level (226 ng/ml), but a low serum magnesium level and a marginally decreased serum cholesterol level. In addition the patient had hypertension, headache and paraesthesia in the oral, palmar and plantar areas. Vision was fully recovered after discontinuation of the cyclosporin treatment and correction of the hypomagnesaemia. Eighteen cases of cortical blindness during cyclosporin treatment are now known in the literature. Hypomagnesaemia appears to be implicated in the pathogenesis.

AB - A 40-year-old man developed cortical blindness during cyclosporin treatment shortly after an allogeneic bone marrow transplantation for chronic myeloid leukaemia. At that time the patient had a therapeutic cyclosporin blood level (226 ng/ml), but a low serum magnesium level and a marginally decreased serum cholesterol level. In addition the patient had hypertension, headache and paraesthesia in the oral, palmar and plantar areas. Vision was fully recovered after discontinuation of the cyclosporin treatment and correction of the hypomagnesaemia. Eighteen cases of cortical blindness during cyclosporin treatment are now known in the literature. Hypomagnesaemia appears to be implicated in the pathogenesis.

UR - https://www.scopus.com/pages/publications/0028099594

M3 - Short survey

C2 - 7935970

AN - SCOPUS:0028099594

SN - 0028-2162

VL - 138

SP - 2057

EP - 2061

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

IS - 41

ER -

Corticale blindheid tijdens behandeling met ciclosporine

Abstract

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