Abstract
Maturity-onset diabetes of the young (MODY) is often misdiagnosed as Type I or II diabetes. This study was designed to assess the cost-effectiveness of MODY screening strategies in Hungary, which included a recent genetic test compared with no routine screening for MODY. A simulation model that combined a decision tree and an individual-level Markov model was constructed to assess the costs per quality-adjusted life year of screening strategies. Stratifying patients based on age and insulin treatment followed by a risk assessment questionnaire, a laboratory test and genetic testing was the most cost-effective strategy, saving EUR 12 and generating 0.0047 quality-adjusted life years gained per screened patient. This screening strategy could be considered for reimbursement, especially in countries with limited resources.
Original language | English |
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Pages (from-to) | 375-385 |
Number of pages | 11 |
Journal | Personalized Medicine |
Volume | 20 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Jul 2023 |
Bibliographical note
Publisher Copyright:© 2023 Future Medicine Ltd.
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Cost-effectiveness of genetic based screening strategies for Maturity Onset Diabetes of the Young (MODY) - Supplementary Material
Kovács, G. (Contributor), Nagy, D. (Contributor), Szilberhorn, L. (Contributor), Zelei, T. (Contributor), Gaál, Z. (Contributor), Vellekoop, H. (Creator), Huygens, S. (Creator), Versteegh, M. (Creator), Mölken, M.R.-V. (Contributor), Koleva-Kolarova, R. (Creator), Tsiachristas, A. (Creator), Wordsworth, S. (Creator) & Nagy, B. (Creator), Future Science Group, 2023
DOI: 10.25402/pme.24117609.v1, https://future-science-group.figshare.com/articles/dataset/Cost-effectiveness_of_genetic_based_screening_strategies_for_Maturity_Onset_Diabetes_of_the_Young_MODY_-_Supplementary_Material/24117609/1
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