Cost-Effectiveness of HIV Treatment as Prevention in Serodiscordant Couples

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To the Editor: We applaud the recent modeling study by Walensky et al. (Oct. 31 issue)(1) as a compelling argument that, in principle, human immunodeficiency virus (HIV) treatment as prevention is cost-effective. However, the authors model only first- and second-order transmissions, thereby ignoring the dynamics of the full sexual network. Recent studies have shown that this modeling approach overestimates the effect of treatment as prevention, because many infections come from other parts of the network.(2),(3) Using the same assumptions regarding the effectiveness of antiretroviral therapy (ART) as Walensky et al., we reran our simulation model of the South African ...
Original languageUndefined/Unknown
Pages (from-to)581-581
Number of pages1
JournalNew England Journal of Medicine
Issue number6
Publication statusPublished - 2014

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  • EMC NIHES-02-65-01

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