Costs of Transcatheter Versus Surgical Aortic Valve Replacement in Intermediate-Risk Patients

Ruben Osnabrugge, Stuart Head, Tessa Genders, Nicolas van Mieghem, Peter de Jaegere, Robert van der Boon, JM Kerkvliet, B Kalesan, Ad Bogers, Arie-Pieter Kappetein, Myriam Hunink

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Background. Transcatheter aortic valve replacement (TAVR) offers a new treatment option for patients with aortic stenosis, but costs may play a decisive role in decision making. Current studies are evaluating TAVR in an intermediate-risk population. We assessed the in-hospital and 1-year follow-up costs of patients undergoing TAVR and surgical aortic valve replacement (SAVR) at intermediate operative risk and identified important cost components. Methods. We prospectively collected clinical data on 141 patients undergoing TAVR and 405 undergoing SAVR. Propensity score matching yielded 42 matched pairs at intermediate risk. Costs were assessed using a detailed resource-use approach and compared using bootstrap methods. Results. In-hospital costs were higher in TAVR patients than in SAVR patients (sic40802 vs sic33354, respectively; p = 0.010). The total costs at 1 year were sic46217 vs sic35511, respectively (p = 0.009). The TAVR was less costly with regard to blood products, operating room use, and length-of-stay. Conclusions. For intermediate-risk patients with severe aortic stenosis the costs at 1 year are higher for TAVR than for SAVR. The difference was mainly caused by the higher costs of the transcatheter valve and was not compensated by the lower costs for blood products and hospital stay in TAVR patients. Therefore, SAVR remains a clinically and economically attractive treatment option. (Ann Thorac Surg 2012;94:1954-60) (C) 2012 by The Society of Thoracic Surgeons
Original languageUndefined/Unknown
Pages (from-to)1954-1960
Number of pages7
JournalAnnals of Thoracic Surgery
Issue number6
Publication statusPublished - 2012

Research programs

  • EMC COEUR-09
  • EMC NIHES-01-64-03
  • EMC NIHES-03-30-02

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