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COVID-19 vaccine hesitancy in Ethiopia: a scoping review for equitable vaccine access

  • Senait Aleamyehu Beshah*
  • , Jibril Bashir Adem
  • , Mosisa Bekele Degefa
  • , Melkamu Ayalew
  • , Yohannes Lakew
  • , Sileshi Garoma
  • , Elizabeth Naa Adukwei Adote
  • , Daniel Malik Achala
  • , Grace Njeri Muriithi
  • , Chinyere Ojiugo Mbachu
  • , James Akazili
  • , Chikezie Ifeanyi
  • , Elias Asfaw Zegeye
  • , Chijioke O Nwosu
  • , John E Ataguba
  • *Corresponding author for this work
  • African Health Economics and Policy Association (AfHEA)
  • Arsi University
  • Ethiopian Ministry of Health
  • University of Nigeria
  • C. K. Tedam University of Technology and Applied Sciences
  • Veritas University Abuja Nigeria Catholic Secretariat Abuja
  • Africa Centers for Disease Control and Prevention (Africa CDC)
  • University of The Free State

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Web of Science)

Abstract

INTRODUCTION: 

COVID-19 vaccines are crucial for preventing severe illness from the virus. Despite their effectiveness; vaccine hesitancy, unequal access, and economic disparities hinder vaccination programs across Africa, posing significant challenges in Ethiopia.

METHOD: 

This scoping review followed the methodological guidelines outlined in the Joanna Briggs Institute Reviewer's and employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses - Extension for Scoping Reviews (PRISMA-ScR) checklist and explanation to ensure transparency. To analyze the data, we developed tailored search strategies for key databases [HINARI, PubMed, Cochrane, African Journals Online (AJOL), and Science Direct] and gray literature sources. These strategies combined controlled vocabulary and relevant keywords. A descriptive thematic analysis was then employed to identify and categorize the various findings within the included studies. The results are presented in a narrative format, summarizing the key themes and providing a clear and comprehensive overview of the current evidence base.

RESULTS AND RECOMMENDATIONS: 

A review of 34 Ethiopian studies revealed significant COVID-19 vaccine hesitancy, with rates exceeding 50% in over 40% of the studies. The lowest hesitancy was found in adults from Addis Ababa (19.1%), while the highest rates were seen among healthcare workers in Oromia (69.7%) and pregnant women in Southwest Ethiopia (68.8%). Factors contributing to vaccine hesitancy in Ethiopia include being female, having only primary education, residing in rural areas, younger age, limited knowledge about the vaccine, reduced trust in authorities, and misperceptions about the risk of the virus. To address this challenge effectively, policymakers should prioritize interventions that build public trust, enhance awareness of the vaccine's benefits, and counter misinformation.

Original languageEnglish
Article number1609752
Number of pages13
JournalFrontiers in Health Services
Volume5
DOIs
Publication statusPublished - 3 Sept 2025
Externally publishedYes

Bibliographical note

© 2025 Beshah, Adem, Degefa, Ayalew, Lakew, Garoma, Adote, Achala, Muriithi, Mbachu, Akazili, Ifeanyi, Zegeye, Nwosu and Ataguba.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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