Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD

DM Yu; CA Mathews; JM Scharf; BM Neale; LK Davis; ER Gamazon; EM Derks; P Evans; CK Edlund; J Crane; L Osiecki; P Gallagher; G Gerber; S Haddad; C Illmann; LM McGrath; C Mayerfeld; S Arepalli; C Barlassina; CL Barr; L Bellodi; F Benarroch; GB Berrio; OJ Bienvenu; DW Black; MH Bloch; H Brentani; RD Bruun; CL Budman; B Camarena; DD Campbell; C Cappi; JCC Silgado; MC Cavallini; DA Chavira; S Chouinard; EH Cook; MR Cookson; V Coric; B Cullen; D Cusi; R Delorme; D Denys; Y Dion; V Eapen; K Egberts; P Falkai; T Fernandez; E Fournier; H Garrido; D Geller; DL Gilbert; SL Girard; HJ Grabe; MA Grados; BD Greenberg; V Gross-Tsur; E Grunblatt; J Hardy; GA Heiman; SMJ Hemmings; LD Herrera; D M Hezel; PJ Hoekstra; J Jankovic; JL Kennedy; RA King; AI Konkashbaev; B Kremeyer; R Kurlan; N Lanzagorta; M Leboyer; JF Leckman; L Lennertz; CY Liu; C Lochner; TL Lowe; S Lupoli; F Macciardi; W Maier; P Manunta; M Marconi; JT McCracken; SCM Restrepo; R Moessner; P Moorjani; J Morgan; H Muller; DL Murphy; AL Naarden; E Nurmi; WC Ochoa; RA Ophoff; AJ Pakstis; MT Pato; CN Pato; J Piacentini; C Pittenger; Y Pollak; SL Rauch; T Renner; VI Reus; MA Richter; MA Riddle; MM Robertson; R Romero; MC Rosario; D Rosenberg; S Ruhrmann; C Sabatti; E Salvi; AS Sampaio; J Samuels; P Sandor; SK Service; B Sheppard; HS Singer; JH Smit; DJ Stein; E Strengman; JA Tischfield; M Turiel; AVV Duarte; H Vallada; J Veenstra-VanderWeele; S Walitza; Y Wang; M Weale; R Weiss; JR Wendland; HGM Westenberg; YY Shugart; AG Hounie; EC Miguel; H Nicolini; M Wagner; A Ruiz-Linares; DC Cath; W McMahon; Daniëlle Posthuma; Ben Oostra; G Nestadt; G A Routeau; S Purcell; MA Jenike; P Heutink; GL Hanna; DV Conti; PD Arnold; NB Freimer; E Stewart; JA Knowles; NJ Cox; DL Pauls

doi:10.1176/appi.ajp.2014.13101306

Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD

DM Yu, CA Mathews, JM Scharf, BM Neale, LK Davis, ER Gamazon, EM Derks, P Evans, CK Edlund, J Crane, L Osiecki, P Gallagher, G Gerber, S Haddad, C Illmann, LM McGrath, C Mayerfeld, S Arepalli, C Barlassina, CL BarrL Bellodi, F Benarroch, GB Berrio, OJ Bienvenu, DW Black, MH Bloch, H Brentani, RD Bruun, CL Budman, B Camarena, DD Campbell, C Cappi, JCC Silgado, MC Cavallini, DA Chavira, S Chouinard, EH Cook, MR Cookson, V Coric, B Cullen, D Cusi, R Delorme, D Denys, Y Dion, V Eapen, K Egberts, P Falkai, T Fernandez, E Fournier, H Garrido, D Geller, DL Gilbert, SL Girard, HJ Grabe, MA Grados, BD Greenberg, V Gross-Tsur, E Grunblatt, J Hardy, GA Heiman, SMJ Hemmings, LD Herrera, D M Hezel, PJ Hoekstra, J Jankovic, JL Kennedy, RA King, AI Konkashbaev, B Kremeyer, R Kurlan, N Lanzagorta, M Leboyer, JF Leckman, L Lennertz, CY Liu, C Lochner, TL Lowe, S Lupoli, F Macciardi, W Maier, P Manunta, M Marconi, JT McCracken, SCM Restrepo, R Moessner, P Moorjani, J Morgan, H Muller, DL Murphy, AL Naarden, E Nurmi, WC Ochoa, RA Ophoff, AJ Pakstis, MT Pato, CN Pato, J Piacentini, C Pittenger, Y Pollak, SL Rauch, T Renner, VI Reus, MA Richter, MA Riddle, MM Robertson, R Romero, MC Rosario, D Rosenberg, S Ruhrmann, C Sabatti, E Salvi, AS Sampaio, J Samuels, P Sandor, SK Service, B Sheppard, HS Singer, JH Smit, DJ Stein, E Strengman, JA Tischfield, M Turiel, AVV Duarte, H Vallada, J Veenstra-VanderWeele, S Walitza, Y Wang, M Weale, R Weiss, JR Wendland, HGM Westenberg, YY Shugart, AG Hounie, EC Miguel, H Nicolini, M Wagner, A Ruiz-Linares, DC Cath, W McMahon, Daniëlle Posthuma, Ben Oostra, G Nestadt, G A Routeau, S Purcell, MA Jenike, P Heutink, GL Hanna, DV Conti, PD Arnold, NB Freimer, E Stewart, JA Knowles, NJ Cox, DL Pauls

Research output: Contribution to journal › Article › Academic › peer-review

94 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	82-93
Number of pages	12
Journal	American Journal of Psychiatry
Volume	172
Issue number	1
DOIs	https://doi.org/10.1176/appi.ajp.2014.13101306
Publication status	Published - 2015

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10.1176/appi.ajp.2014.13101306

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Yu, DM., Mathews, CA., Scharf, JM., Neale, BM., Davis, LK., Gamazon, ER., Derks, EM., Evans, P., Edlund, CK., Crane, J., Osiecki, L., Gallagher, P., Gerber, G., Haddad, S., Illmann, C., McGrath, LM., Mayerfeld, C., Arepalli, S., Barlassina, C., ... Pauls, DL. (2015). Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD. American Journal of Psychiatry, 172(1), 82-93. https://doi.org/10.1176/appi.ajp.2014.13101306

Yu, DM ; Mathews, CA ; Scharf, JM ; Neale, BM ; Davis, LK ; Gamazon, ER ; Derks, EM ; Evans, P ; Edlund, CK ; Crane, J ; Osiecki, L ; Gallagher, P ; Gerber, G ; Haddad, S ; Illmann, C ; McGrath, LM ; Mayerfeld, C ; Arepalli, S ; Barlassina, C ; Barr, CL ; Bellodi, L ; Benarroch, F ; Berrio, GB ; Bienvenu, OJ ; Black, DW ; Bloch, MH ; Brentani, H ; Bruun, RD ; Budman, CL ; Camarena, B ; Campbell, DD ; Cappi, C ; Silgado, JCC ; Cavallini, MC ; Chavira, DA ; Chouinard, S ; Cook, EH ; Cookson, MR ; Coric, V ; Cullen, B ; Cusi, D ; Delorme, R ; Denys, D ; Dion, Y ; Eapen, V ; Egberts, K ; Falkai, P ; Fernandez, T ; Fournier, E ; Garrido, H ; Geller, D ; Gilbert, DL ; Girard, SL ; Grabe, HJ ; Grados, MA ; Greenberg, BD ; Gross-Tsur, V ; Grunblatt, E ; Hardy, J ; Heiman, GA ; Hemmings, SMJ ; Herrera, LD ; Hezel, D M ; Hoekstra, PJ ; Jankovic, J ; Kennedy, JL ; King, RA ; Konkashbaev, AI ; Kremeyer, B ; Kurlan, R ; Lanzagorta, N ; Leboyer, M ; Leckman, JF ; Lennertz, L ; Liu, CY ; Lochner, C ; Lowe, TL ; Lupoli, S ; Macciardi, F ; Maier, W ; Manunta, P ; Marconi, M ; McCracken, JT ; Restrepo, SCM ; Moessner, R ; Moorjani, P ; Morgan, J ; Muller, H ; Murphy, DL ; Naarden, AL ; Nurmi, E ; Ochoa, WC ; Ophoff, RA ; Pakstis, AJ ; Pato, MT ; Pato, CN ; Piacentini, J ; Pittenger, C ; Pollak, Y ; Rauch, SL ; Renner, T ; Reus, VI ; Richter, MA ; Riddle, MA ; Robertson, MM ; Romero, R ; Rosario, MC ; Rosenberg, D ; Ruhrmann, S ; Sabatti, C ; Salvi, E ; Sampaio, AS ; Samuels, J ; Sandor, P ; Service, SK ; Sheppard, B ; Singer, HS ; Smit, JH ; Stein, DJ ; Strengman, E ; Tischfield, JA ; Turiel, M ; Duarte, AVV ; Vallada, H ; Veenstra-VanderWeele, J ; Walitza, S ; Wang, Y ; Weale, M ; Weiss, R ; Wendland, JR ; Westenberg, HGM ; Shugart, YY ; Hounie, AG ; Miguel, EC ; Nicolini, H ; Wagner, M ; Ruiz-Linares, A ; Cath, DC ; McMahon, W ; Posthuma, Daniëlle ; Oostra, Ben ; Nestadt, G ; Routeau, G A ; Purcell, S ; Jenike, MA ; Heutink, P ; Hanna, GL ; Conti, DV ; Arnold, PD ; Freimer, NB ; Stewart, E ; Knowles, JA ; Cox, NJ ; Pauls, DL. / Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD. In: American Journal of Psychiatry. 2015 ; Vol. 172, No. 1. pp. 82-93.

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title = "Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD",

author = "DM Yu and CA Mathews and JM Scharf and BM Neale and LK Davis and ER Gamazon and EM Derks and P Evans and CK Edlund and J Crane and L Osiecki and P Gallagher and G Gerber and S Haddad and C Illmann and LM McGrath and C Mayerfeld and S Arepalli and C Barlassina and CL Barr and L Bellodi and F Benarroch and GB Berrio and OJ Bienvenu and DW Black and MH Bloch and H Brentani and RD Bruun and CL Budman and B Camarena and DD Campbell and C Cappi and JCC Silgado and MC Cavallini and DA Chavira and S Chouinard and EH Cook and MR Cookson and V Coric and B Cullen and D Cusi and R Delorme and D Denys and Y Dion and V Eapen and K Egberts and P Falkai and T Fernandez and E Fournier and H Garrido and D Geller and DL Gilbert and SL Girard and HJ Grabe and MA Grados and BD Greenberg and V Gross-Tsur and E Grunblatt and J Hardy and GA Heiman and SMJ Hemmings and LD Herrera and Hezel, {D M} and PJ Hoekstra and J Jankovic and JL Kennedy and RA King and AI Konkashbaev and B Kremeyer and R Kurlan and N Lanzagorta and M Leboyer and JF Leckman and L Lennertz and CY Liu and C Lochner and TL Lowe and S Lupoli and F Macciardi and W Maier and P Manunta and M Marconi and JT McCracken and SCM Restrepo and R Moessner and P Moorjani and J Morgan and H Muller and DL Murphy and AL Naarden and E Nurmi and WC Ochoa and RA Ophoff and AJ Pakstis and MT Pato and CN Pato and J Piacentini and C Pittenger and Y Pollak and SL Rauch and T Renner and VI Reus and MA Richter and MA Riddle and MM Robertson and R Romero and MC Rosario and D Rosenberg and S Ruhrmann and C Sabatti and E Salvi and AS Sampaio and J Samuels and P Sandor and SK Service and B Sheppard and HS Singer and JH Smit and DJ Stein and E Strengman and JA Tischfield and M Turiel and AVV Duarte and H Vallada and J Veenstra-VanderWeele and S Walitza and Y Wang and M Weale and R Weiss and JR Wendland and HGM Westenberg and YY Shugart and AG Hounie and EC Miguel and H Nicolini and M Wagner and A Ruiz-Linares and DC Cath and W McMahon and Dani{\"e}lle Posthuma and Ben Oostra and G Nestadt and Routeau, {G A} and S Purcell and MA Jenike and P Heutink and GL Hanna and DV Conti and PD Arnold and NB Freimer and E Stewart and JA Knowles and NJ Cox and DL Pauls",

year = "2015",

doi = "10.1176/appi.ajp.2014.13101306",

language = "Undefined/Unknown",

volume = "172",

pages = "82--93",

journal = "American Journal of Psychiatry",

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Yu, DM, Mathews, CA, Scharf, JM, Neale, BM, Davis, LK, Gamazon, ER, Derks, EM, Evans, P, Edlund, CK, Crane, J, Osiecki, L, Gallagher, P, Gerber, G, Haddad, S, Illmann, C, McGrath, LM, Mayerfeld, C, Arepalli, S, Barlassina, C, Barr, CL, Bellodi, L, Benarroch, F, Berrio, GB, Bienvenu, OJ, Black, DW, Bloch, MH, Brentani, H, Bruun, RD, Budman, CL, Camarena, B, Campbell, DD, Cappi, C, Silgado, JCC, Cavallini, MC, Chavira, DA, Chouinard, S, Cook, EH, Cookson, MR, Coric, V, Cullen, B, Cusi, D, Delorme, R, Denys, D, Dion, Y, Eapen, V, Egberts, K, Falkai, P, Fernandez, T, Fournier, E, Garrido, H, Geller, D, Gilbert, DL, Girard, SL, Grabe, HJ, Grados, MA, Greenberg, BD, Gross-Tsur, V, Grunblatt, E, Hardy, J, Heiman, GA, Hemmings, SMJ, Herrera, LD, Hezel, DM, Hoekstra, PJ, Jankovic, J, Kennedy, JL, King, RA, Konkashbaev, AI, Kremeyer, B, Kurlan, R, Lanzagorta, N, Leboyer, M, Leckman, JF, Lennertz, L, Liu, CY, Lochner, C, Lowe, TL, Lupoli, S, Macciardi, F, Maier, W, Manunta, P, Marconi, M, McCracken, JT, Restrepo, SCM, Moessner, R, Moorjani, P, Morgan, J, Muller, H, Murphy, DL, Naarden, AL, Nurmi, E, Ochoa, WC, Ophoff, RA, Pakstis, AJ, Pato, MT, Pato, CN, Piacentini, J, Pittenger, C, Pollak, Y, Rauch, SL, Renner, T, Reus, VI, Richter, MA, Riddle, MA, Robertson, MM, Romero, R, Rosario, MC, Rosenberg, D, Ruhrmann, S, Sabatti, C, Salvi, E, Sampaio, AS, Samuels, J, Sandor, P, Service, SK, Sheppard, B, Singer, HS, Smit, JH, Stein, DJ, Strengman, E, Tischfield, JA, Turiel, M, Duarte, AVV, Vallada, H, Veenstra-VanderWeele, J, Walitza, S, Wang, Y, Weale, M, Weiss, R, Wendland, JR, Westenberg, HGM, Shugart, YY, Hounie, AG, Miguel, EC, Nicolini, H, Wagner, M, Ruiz-Linares, A, Cath, DC, McMahon, W, Posthuma, D, Oostra, B, Nestadt, G, Routeau, GA, Purcell, S, Jenike, MA, Heutink, P, Hanna, GL, Conti, DV, Arnold, PD, Freimer, NB, Stewart, E, Knowles, JA, Cox, NJ & Pauls, DL 2015, 'Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD', American Journal of Psychiatry, vol. 172, no. 1, pp. 82-93. https://doi.org/10.1176/appi.ajp.2014.13101306

Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD. / Yu, DM; Mathews, CA; Scharf, JM; Neale, BM; Davis, LK; Gamazon, ER; Derks, EM; Evans, P; Edlund, CK; Crane, J; Osiecki, L; Gallagher, P; Gerber, G; Haddad, S; Illmann, C; McGrath, LM; Mayerfeld, C; Arepalli, S; Barlassina, C; Barr, CL; Bellodi, L; Benarroch, F; Berrio, GB; Bienvenu, OJ; Black, DW; Bloch, MH; Brentani, H; Bruun, RD; Budman, CL; Camarena, B; Campbell, DD; Cappi, C; Silgado, JCC; Cavallini, MC; Chavira, DA; Chouinard, S; Cook, EH; Cookson, MR; Coric, V; Cullen, B; Cusi, D; Delorme, R; Denys, D; Dion, Y; Eapen, V; Egberts, K; Falkai, P; Fernandez, T; Fournier, E; Garrido, H; Geller, D; Gilbert, DL; Girard, SL; Grabe, HJ; Grados, MA; Greenberg, BD; Gross-Tsur, V; Grunblatt, E; Hardy, J; Heiman, GA; Hemmings, SMJ; Herrera, LD; Hezel, D M; Hoekstra, PJ; Jankovic, J; Kennedy, JL; King, RA; Konkashbaev, AI; Kremeyer, B; Kurlan, R; Lanzagorta, N; Leboyer, M; Leckman, JF; Lennertz, L; Liu, CY; Lochner, C; Lowe, TL; Lupoli, S; Macciardi, F; Maier, W; Manunta, P; Marconi, M; McCracken, JT; Restrepo, SCM; Moessner, R; Moorjani, P; Morgan, J; Muller, H; Murphy, DL; Naarden, AL; Nurmi, E; Ochoa, WC; Ophoff, RA; Pakstis, AJ; Pato, MT; Pato, CN; Piacentini, J; Pittenger, C; Pollak, Y; Rauch, SL; Renner, T; Reus, VI; Richter, MA; Riddle, MA; Robertson, MM; Romero, R; Rosario, MC; Rosenberg, D; Ruhrmann, S; Sabatti, C; Salvi, E; Sampaio, AS; Samuels, J; Sandor, P; Service, SK; Sheppard, B; Singer, HS; Smit, JH; Stein, DJ; Strengman, E; Tischfield, JA; Turiel, M; Duarte, AVV; Vallada, H; Veenstra-VanderWeele, J; Walitza, S; Wang, Y; Weale, M; Weiss, R; Wendland, JR; Westenberg, HGM; Shugart, YY; Hounie, AG; Miguel, EC; Nicolini, H; Wagner, M; Ruiz-Linares, A; Cath, DC; McMahon, W; Posthuma, Daniëlle; Oostra, Ben; Nestadt, G; Routeau, G A; Purcell, S; Jenike, MA; Heutink, P; Hanna, GL; Conti, DV; Arnold, PD; Freimer, NB; Stewart, E; Knowles, JA; Cox, NJ; Pauls, DL.

In: American Journal of Psychiatry, Vol. 172, No. 1, 2015, p. 82-93.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD

AU - Yu, DM

AU - Mathews, CA

AU - Scharf, JM

AU - Neale, BM

AU - Davis, LK

AU - Gamazon, ER

AU - Derks, EM

AU - Evans, P

AU - Edlund, CK

AU - Crane, J

AU - Osiecki, L

AU - Gallagher, P

AU - Gerber, G

AU - Haddad, S

AU - Illmann, C

AU - McGrath, LM

AU - Mayerfeld, C

AU - Arepalli, S

AU - Barlassina, C

AU - Barr, CL

AU - Bellodi, L

AU - Benarroch, F

AU - Berrio, GB

AU - Bienvenu, OJ

AU - Black, DW

AU - Bloch, MH

AU - Brentani, H

AU - Bruun, RD

AU - Budman, CL

AU - Camarena, B

AU - Campbell, DD

AU - Cappi, C

AU - Silgado, JCC

AU - Cavallini, MC

AU - Chavira, DA

AU - Chouinard, S

AU - Cook, EH

AU - Cookson, MR

AU - Coric, V

AU - Cullen, B

AU - Cusi, D

AU - Delorme, R

AU - Denys, D

AU - Dion, Y

AU - Eapen, V

AU - Egberts, K

AU - Falkai, P

AU - Fernandez, T

AU - Fournier, E

AU - Garrido, H

AU - Geller, D

AU - Gilbert, DL

AU - Girard, SL

AU - Grabe, HJ

AU - Grados, MA

AU - Greenberg, BD

AU - Gross-Tsur, V

AU - Grunblatt, E

AU - Hardy, J

AU - Heiman, GA

AU - Hemmings, SMJ

AU - Herrera, LD

AU - Hezel, D M

AU - Hoekstra, PJ

AU - Jankovic, J

AU - Kennedy, JL

AU - King, RA

AU - Konkashbaev, AI

AU - Kremeyer, B

AU - Kurlan, R

AU - Lanzagorta, N

AU - Leboyer, M

AU - Leckman, JF

AU - Lennertz, L

AU - Liu, CY

AU - Lochner, C

AU - Lowe, TL

AU - Lupoli, S

AU - Macciardi, F

AU - Maier, W

AU - Manunta, P

AU - Marconi, M

AU - McCracken, JT

AU - Restrepo, SCM

AU - Moessner, R

AU - Moorjani, P

AU - Morgan, J

AU - Muller, H

AU - Murphy, DL

AU - Naarden, AL

AU - Nurmi, E

AU - Ochoa, WC

AU - Ophoff, RA

AU - Pakstis, AJ

AU - Pato, MT

AU - Pato, CN

AU - Piacentini, J

AU - Pittenger, C

AU - Pollak, Y

AU - Rauch, SL

AU - Renner, T

AU - Reus, VI

AU - Richter, MA

AU - Riddle, MA

AU - Robertson, MM

AU - Romero, R

AU - Rosario, MC

AU - Rosenberg, D

AU - Ruhrmann, S

AU - Sabatti, C

AU - Salvi, E

AU - Sampaio, AS

AU - Samuels, J

AU - Sandor, P

AU - Service, SK

AU - Sheppard, B

AU - Singer, HS

AU - Smit, JH

AU - Stein, DJ

AU - Strengman, E

AU - Tischfield, JA

AU - Turiel, M

AU - Duarte, AVV

AU - Vallada, H

AU - Veenstra-VanderWeele, J

AU - Walitza, S

AU - Wang, Y

AU - Weale, M

AU - Weiss, R

AU - Wendland, JR

AU - Westenberg, HGM

AU - Shugart, YY

AU - Hounie, AG

AU - Miguel, EC

AU - Nicolini, H

AU - Wagner, M

AU - Ruiz-Linares, A

AU - Cath, DC

AU - McMahon, W

AU - Posthuma, Daniëlle

AU - Oostra, Ben

AU - Nestadt, G

AU - Routeau, G A

AU - Purcell, S

AU - Jenike, MA

AU - Heutink, P

AU - Hanna, GL

AU - Conti, DV

AU - Arnold, PD

AU - Freimer, NB

AU - Stewart, E

AU - Knowles, JA

AU - Cox, NJ

AU - Pauls, DL

PY - 2015

Y1 - 2015

U2 - 10.1176/appi.ajp.2014.13101306

DO - 10.1176/appi.ajp.2014.13101306

M3 - Article

VL - 172

SP - 82

EP - 93

JO - American Journal of Psychiatry

JF - American Journal of Psychiatry

SN - 0002-953X

IS - 1

ER -