Cryptic SARS-CoV-2 lineage identified on two mink farms as a possible result of long-term undetected circulation in an unknown animal reservoir, Poland, November 2022 to January 2023

Katarzyna Domańska-Blicharz*, Bas B. Oude Munnink, Anna Orłowska, Marcin Smreczak, Justyna Opolska, Anna Lisowska, Paweł Trębas, Wojciech Socha, Aleksandra Giza, Arkadiusz Bomba, Ewelina Iwan, Jerzy Rola, Marion Koopmans

*Corresponding author for this work

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Abstract

In late 2022 and early 2023, SARS-CoV-2 infections were detected on three mink farms in Poland situated within a few km from each other. Whole-genome sequencing of the viruses on two of the farms showed that they were related to a virus identified in humans in the same region 2 years before (B.1.1.307 lineage). Many mutations were found, including in the S protein typical of adaptations to the mink host. The origin of the virus remains to be determined.

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