Current perspectives on diagnosis and management of sternal wound infections

Erlangga Yusuf, Monica Chan, Nora Renz, Andrej Trampuz

Research output: Contribution to journalReview articleAcademicpeer-review

38 Citations (Scopus)
2 Downloads (Pure)


Deep sternal wound infection (DSWI), also known as mediastinitis, is a serious and potentially fatal condition. The diagnosis and treatment of DSWI are challenging. In this current narrative review, the epidemiology, risk factors, diagnosis, and surgical and antimicrobial management of DSWI are discussed. Ideally, the management of DSWI requires early and sufficient surgical debridement and appropriate antibiotic therapy. When foreign material is present, biofilm-active antibiotic therapy is also needed. Because DSWI is often complex, the management requires the involvement of a multidisciplinary team consisting of cardiothoracic surgeons, plastic surgeons, intensivists, infectious disease specialists, and clinical microbiologists.

Original languageEnglish
Pages (from-to)961-968
Number of pages8
JournalInfection and Drug Resistance
Publication statusPublished - 16 Jul 2018
Externally publishedYes


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