Dairy consumption and 3-year risk of type 2 diabetes after myocardial infarction: A prospective analysis in the alpha omega cohort

Maria G. Jacobo Cejudo*, Esther Cruijsen, Christiane Heuser, Sabita S. Soedamah-Muthu, Trudy Voortman, Johanna M. Geleijnse

*Corresponding author for this work

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Abstract

Population-based studies suggest a role for dairy, especially yogurt, in the prevention of type 2 diabetes (T2D). Whether dairy affects T2D risk after myocardial infarction (MI) is unknown. We examined associations of (types of) dairy with T2D incidence in drug-treated, post-MI patients from the Alpha Omega Cohort. The analysis included 3401 patients (80% men) aged 60–80 y who were free of T2D at baseline (2002–2006). Dairy intakes were assessed using a validated food-frequency questionnaire. Incident T2D was ascertained through self-reported physician diagnosis and/or medication use. Multivariable Cox models were used to calculate Hazard ratios (HRs) and 95% confidence intervals (CI) for T2D with dairy intake in categories and per 1-standard deviation (SD) increment. Most patients consumed dairy, and median intakes were 264 g/d for total dairy, 82 g/d for milk and 41 g/d for yogurt. During 40 months of follow-up (10,714 person-years), 186 patients developed T2D. After adjustment for confounders, including diet, HRs per 1-SD were 1.06 (95% CI 0.91–1.22) for total dairy, 1.02 (0.88–1.18) for milk and 1.04 (0.90–1.20) for yogurt. Associations were also absent for other dairy types and in dairy categories (all p-trend > 0.05). Our findings suggest no major role for dairy consumption in T2D prevention after MI.

Original languageEnglish
Article number3146
Number of pages13
JournalNutrients
Volume13
Issue number9
DOIs
Publication statusPublished - 9 Sep 2021

Bibliographical note

Funding Information:
M.G.J.C. is funded by The Mexican National Council for Science and Technology (CONA-CYT) through its Graduate Programme “Becas de posgrado en el Extranjero”. Data collection and follow-up of the Alpha Omega Trial (2002–2009), from which The Alpha Omega Cohort emerged, was funded by the Dutch Heart Foundation (grant no. 200T401), and the US National Institutes of Health (NIH/NHLBI grant no. R01HL076200). The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

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