Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy

Minke A. E. Rab, Jennifer Bos, Brigitte A. van Oirschot, H.A.S. (Stéphanie) van Straaten, Penelope A. Kosinski, Victor Chubukov, Hyeryun Kim, Heidi Mangus, Roger E. G. Schutgens, Gerard Pasterkamp, Lenny Dang, Charles Kung, Eduard J. van Beers, Richard van Wijk*

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

33 Citations (Web of Science)
69 Downloads (Pure)
Original languageEnglish
Pages (from-to)2997-3001
Number of pages5
JournalBlood
Volume137
Issue number21
DOIs
Publication statusPublished - 27 May 2021

Bibliographical note

Funding Information:
This research has been funded, in part, by Agios Pharmaceuticals Inc and the Eurostars Program (SCOOP, ESTAR18105).

Research programs

  • EMC MM-02-54-03

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