Design of a Privacy-Preserving ETL Dataflow for Federated ICU Data Reuse in INDICATE

The INDICATE project, funded by the European Union under the Digital Europe Programme, develops a federated framework for the secure reuse of intensive care unit (ICU) data within the EHDS. This work presents the design of a privacy-preserving ETL dataflow that standardizes and validates ICU data locally. The process enables harmonization of ICU data into the OMOP Common Data Model, based on HL7 FHIR as well, ensuring semantic interoperability, data quality, and regulatory compliance. Only aggregated study results are uploaded to the INDICATE Portal, ensuring that no patient-level data leave the hospital domain.