Desmoplastic infantile ganglioglioma with a malignant course

EW Hoving, J.M. Kros, E Groninger, WFA den Dunnen

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28 Citations (Scopus)


Desmoplastic infantile gangliogliomas (DIGs) are rare supratentorial tumors that arise in infancy. Despite the large size of these lesions, the prognosis is generally considered favorable after gross-total resection (GTR); however, in incidental cases tumor progression has been described. The authors report on a child harboring a DIG with a high-grade primitive cell population and glial differentiation. The progressive clinical course was determined by this cell component in spite of GTR and adjuvant chemotherapy. The significance of the presence of a high-grade primitive tumor component in the context of DIG is discussed.
Original languageUndefined/Unknown
Pages (from-to)95-98
Number of pages4
JournalJournal of Neurosurgery-Pediatrics
Issue number1
Publication statusPublished - 2008

Research programs

  • EMC MM-03-24-01
  • EMC MM-03-44-06

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