Detection of norovirus variant GII.4 Hong Kong in Asia and Europe, 2017?2019

MCW Chan, S Roy, J Bonifacio, LY Zhang, P Chhabra, JCN Chan, C Celma, MA Igoy, SL Lau, KN Mohammad, J Vinjé, H Vennema, J Breuer, Marion Koopmans, Miranda de Graaf

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)


We report a new norovirus GII.4 variant, GII.4 Hong Kong, with low-level circulation in 4 Eurasia countries since mid-2017. Amino acid substitutions in key residues on the virus capsid associated with the emergence of pandemic noroviruses suggest that GII.4 Hong Kong has the potential to become the next pandemic variant.

Original languageEnglish
Pages (from-to)289-293
Number of pages5
JournalEmerging Infectious Diseases
Issue number1
Publication statusPublished - Jan 2021

Bibliographical note

Funding Information:
This work was supported in part by the commissioned Health and Medical Research Fund of the HKSAR Government (CU-15-C2 to M.C.-W.C.) and the Wellcome Trust (203268/Z/16/Z to J.B.). M.d.G was funded through METASTAVA (grant no. 773830).

Publisher Copyright:
© 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.

Research programs

  • EMC OR-01


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