Detection of novel divergent arenaviruses in bold snakes with inclusion body disease in The Netherlands

Rogier Bodewes, MJL Kik, Stalinraj Victor, Claudia Schapendonk, Bart Haagmans, Saskia Smits, Ab Osterhaus

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Abstract

Arenaviruses are bi-segmented negative-stranded RNA viruses, which were until recently only detected in rodents and humans. Now highly divergent arenaviruses have been identified in boid snakes with inclusion body disease (IBD). Here, we describe the identification of a new species and variants of the highly divergent arenaviruses, which were detected in tissues of captive boid snakes with IBD in The Netherlands by next-generation sequencing. Phylogenetic analysis of the complete sequence of the open reading frames of the four predicted proteins of one of the detected viruses revealed that this virus was most closely related to the recently identified Golden Gate virus, while considerable sequence differences were observed between the highly divergent arenaviruses detected in this study. These findings add to the recent identification of the highly divergent arenaviruses in boid snakes with IBD in the United States and indicate that these viruses also circulate among boid snakes in Europe.
Original languageUndefined/Unknown
Pages (from-to)1206-1210
Number of pages5
JournalJournal of General Virology
Volume94
DOIs
Publication statusPublished - 2013

Research programs

  • EMC MM-04-27-01

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