Developments in care for patients with pancreatic cancer

Simone Augustinus, Olivier R. Busch, Bert A. Bonsing, Marco J. Bruno, Jan Willem B. de Groot, Bas Groot Koerkamp, Martijn P.W. Intven, Frank Köhler, Quintus Molenaar, Johanna W. Wilmink, Marc G. Besselink

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

In the past years several developments have occurred in the care for patients with pancreatic cancer in the Netherlands. New palliative chemotherapy strategies using FOLFRINOX or gemcitabine/nab-paclitaxel were introduced for patients with advanced disease. Due to centralization of pancreatic surgery, introduction of neoadjuvant therapy, and the implementation of standardized postoperative care more patients became enable for resection, postoperative mortality decreased, and survival improved. Within the randomized PREOPANC trial of the Dutch Pancreatic Cancer Group (DPCG), neoadjuvant therapy using chemoradiation for (borderline) resectable pancreatic cancer improved five-year survival from 7% to 21%. Furthermore, due to nationwide training programs, the use of minimally invasive surgery has increased. Regardless of these developments, the survival of patients with pancreatic cancer is still low and 61% of Dutch patients with pancreatic cancer patients do not receive any tumor targeted therapy. The DPCG is active to improve quality of care through auditing, research, guideline development, and education.

Original languageEnglish
Article numberD7435
JournalNederlands Tijdschrift voor Geneeskunde
Volume167
Issue number47
Publication statusPublished - 20 Nov 2023

Bibliographical note

Publisher Copyright:
© 2023, Bohn Stafleu van Loghum. All rights reserved.

Fingerprint

Dive into the research topics of 'Developments in care for patients with pancreatic cancer'. Together they form a unique fingerprint.

Cite this