TY - JOUR
T1 - Diagnosis, prognostic factors, and assessment of ALL in adults
T2 - 2024 ELN recommendations from a European expert panel
AU - Gökbuget, Nicola
AU - Boissel, Nicolas
AU - Chiaretti, Sabina
AU - Dombret, Herve
AU - Doubek, Michael
AU - Fielding, Adele
AU - Foa, Robin
AU - Giebel, Sebastian
AU - Hoelzer, Dieter
AU - Hunault, Mathilde
AU - Marks, David I.
AU - Martinelli, Giovanni
AU - Ottmann, Oliver
AU - Rijneveld, Anita
AU - Rousselot, Philippe
AU - Ribera, Josep
AU - Bassan, Renato
N1 - Publisher Copyright:
© 2024 American Society of Hematology
PY - 2024/5/9
Y1 - 2024/5/9
N2 - Working groups of the European Leukemia Net have published several important consensus guidelines. Acute lymphoblastic leukemia (ALL) has many different clinical and biological subgroups and the knowledge on disease biology and therapeutic options is increasing exponentially. The European Working Group for Adult ALL has therefore summarized the current state of the art and provided comprehensive consensus recommendations for diagnostic approaches, biologic and clinical characterization, prognostic factors, and risk stratification as well as definitions of endpoints and outcomes. Aspects of treatment, management of subgroups and specific situations, aftercare, and supportive care are covered in a separate publication. The present recommendation intends to provide guidance for the initial management of adult patients with ALL and to define principles as a basis for future collaborative research.
AB - Working groups of the European Leukemia Net have published several important consensus guidelines. Acute lymphoblastic leukemia (ALL) has many different clinical and biological subgroups and the knowledge on disease biology and therapeutic options is increasing exponentially. The European Working Group for Adult ALL has therefore summarized the current state of the art and provided comprehensive consensus recommendations for diagnostic approaches, biologic and clinical characterization, prognostic factors, and risk stratification as well as definitions of endpoints and outcomes. Aspects of treatment, management of subgroups and specific situations, aftercare, and supportive care are covered in a separate publication. The present recommendation intends to provide guidance for the initial management of adult patients with ALL and to define principles as a basis for future collaborative research.
UR - http://www.scopus.com/inward/record.url?scp=85186692475&partnerID=8YFLogxK
U2 - 10.1182/blood.2023020794
DO - 10.1182/blood.2023020794
M3 - Comment/Letter to the editor
C2 - 38295337
AN - SCOPUS:85186692475
SN - 0006-4971
VL - 143
SP - 1891
EP - 1902
JO - Blood
JF - Blood
IS - 19
ER -