Diagnosis, prognostic factors, and assessment of ALL in adults: 2024 ELN recommendations from a European expert panel

Nicola Gökbuget*, Nicolas Boissel, Sabina Chiaretti, Herve Dombret, Michael Doubek, Adele Fielding, Robin Foa, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

14 Citations (Scopus)

Abstract

Working groups of the European Leukemia Net have published several important consensus guidelines. Acute lymphoblastic leukemia (ALL) has many different clinical and biological subgroups and the knowledge on disease biology and therapeutic options is increasing exponentially. The European Working Group for Adult ALL has therefore summarized the current state of the art and provided comprehensive consensus recommendations for diagnostic approaches, biologic and clinical characterization, prognostic factors, and risk stratification as well as definitions of endpoints and outcomes. Aspects of treatment, management of subgroups and specific situations, aftercare, and supportive care are covered in a separate publication. The present recommendation intends to provide guidance for the initial management of adult patients with ALL and to define principles as a basis for future collaborative research.

Original languageEnglish
Pages (from-to)1891-1902
Number of pages12
JournalBlood
Volume143
Issue number19
Early online date31 Jan 2024
DOIs
Publication statusPublished - 9 May 2024

Bibliographical note

Publisher Copyright:
© 2024 American Society of Hematology

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