Diagnostic value of blind synovial biopsy in clinical practice

EJA Kroot; Angelique Weel; Mieke Hazes; Pieter Zondervan; Rien Heijboer; Paul van Daele; Radboud Dolhain

doi:10.1093/rheumatology/kei117

Diagnostic value of blind synovial biopsy in clinical practice

EJA Kroot^*, Angelique Weel, Mieke Hazes, Pieter Zondervan, Rien Heijboer, Paul van Daele, Radboud Dolhain

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

Abstract

OBJECTIVE: To assess the diagnostic value of blindly performed synovial biopsies in carefully selected patients with unclassified arthritis.

METHODS: Synovial tissue was obtained blindly under local anaesthesia. The Arthroforce III take-apart 3.5 mm needle and 1.5 mm grasping forceps were used for this purpose.

RESULTS: Four patients with unclassified arthritis could be diagnosed properly based upon examination of synovial tissue of the knee obtained by an easy-to-perform blind biopsy. The arthritis of the four patients was diagnosed as being part of Erdheim-Chester disease, sarcoidosis, multicentric reticulohistiocytosis and arthritis caused by foreign-body material, respectively.

CONCLUSIONS: Analysis of synovial tissue obtained during a blind biopsy procedure has diagnostic potential in carefully selected patients with unclassified arthritis. The common denominator in all the cases presented was a differential diagnosis consisting of a rheumatological disease with characteristic histological features.

Original language	English
Pages (from-to)	192-195
Number of pages	4
Journal	Rheumatology
Volume	45
Issue number	2
DOIs	https://doi.org/10.1093/rheumatology/kei117
Publication status	Published - Feb 2006

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EMC MM-03-24-01
EMC MUSC-01-31-01
EMC MUSC-01-51-01

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10.1093/rheumatology/kei117

http://hdl.handle.net/1765/70771

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title = "Diagnostic value of blind synovial biopsy in clinical practice",

abstract = "OBJECTIVE: To assess the diagnostic value of blindly performed synovial biopsies in carefully selected patients with unclassified arthritis.METHODS: Synovial tissue was obtained blindly under local anaesthesia. The Arthroforce III take-apart 3.5 mm needle and 1.5 mm grasping forceps were used for this purpose.RESULTS: Four patients with unclassified arthritis could be diagnosed properly based upon examination of synovial tissue of the knee obtained by an easy-to-perform blind biopsy. The arthritis of the four patients was diagnosed as being part of Erdheim-Chester disease, sarcoidosis, multicentric reticulohistiocytosis and arthritis caused by foreign-body material, respectively.CONCLUSIONS: Analysis of synovial tissue obtained during a blind biopsy procedure has diagnostic potential in carefully selected patients with unclassified arthritis. The common denominator in all the cases presented was a differential diagnosis consisting of a rheumatological disease with characteristic histological features.",

author = "EJA Kroot and Angelique Weel and Mieke Hazes and Pieter Zondervan and Rien Heijboer and {van Daele}, Paul and Radboud Dolhain",

year = "2006",

month = feb,

doi = "10.1093/rheumatology/kei117",

language = "English",

volume = "45",

pages = "192--195",

journal = "Rheumatology",

issn = "1462-0324",

publisher = "Oxford University Press",

number = "2",

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TY - JOUR

T1 - Diagnostic value of blind synovial biopsy in clinical practice

AU - Kroot, EJA

AU - Weel, Angelique

AU - Hazes, Mieke

AU - Zondervan, Pieter

AU - Heijboer, Rien

AU - van Daele, Paul

AU - Dolhain, Radboud

PY - 2006/2

Y1 - 2006/2

N2 - OBJECTIVE: To assess the diagnostic value of blindly performed synovial biopsies in carefully selected patients with unclassified arthritis.METHODS: Synovial tissue was obtained blindly under local anaesthesia. The Arthroforce III take-apart 3.5 mm needle and 1.5 mm grasping forceps were used for this purpose.RESULTS: Four patients with unclassified arthritis could be diagnosed properly based upon examination of synovial tissue of the knee obtained by an easy-to-perform blind biopsy. The arthritis of the four patients was diagnosed as being part of Erdheim-Chester disease, sarcoidosis, multicentric reticulohistiocytosis and arthritis caused by foreign-body material, respectively.CONCLUSIONS: Analysis of synovial tissue obtained during a blind biopsy procedure has diagnostic potential in carefully selected patients with unclassified arthritis. The common denominator in all the cases presented was a differential diagnosis consisting of a rheumatological disease with characteristic histological features.

AB - OBJECTIVE: To assess the diagnostic value of blindly performed synovial biopsies in carefully selected patients with unclassified arthritis.METHODS: Synovial tissue was obtained blindly under local anaesthesia. The Arthroforce III take-apart 3.5 mm needle and 1.5 mm grasping forceps were used for this purpose.RESULTS: Four patients with unclassified arthritis could be diagnosed properly based upon examination of synovial tissue of the knee obtained by an easy-to-perform blind biopsy. The arthritis of the four patients was diagnosed as being part of Erdheim-Chester disease, sarcoidosis, multicentric reticulohistiocytosis and arthritis caused by foreign-body material, respectively.CONCLUSIONS: Analysis of synovial tissue obtained during a blind biopsy procedure has diagnostic potential in carefully selected patients with unclassified arthritis. The common denominator in all the cases presented was a differential diagnosis consisting of a rheumatological disease with characteristic histological features.

U2 - 10.1093/rheumatology/kei117

DO - 10.1093/rheumatology/kei117

M3 - Article

C2 - 16234280

SN - 1462-0324

VL - 45

SP - 192

EP - 195

JO - Rheumatology

JF - Rheumatology

IS - 2

ER -

Diagnostic value of blind synovial biopsy in clinical practice

Abstract

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