Do socio-demographic factors modify the effect of weather on malaria in Kanungu District, Uganda?

Bwindi Community Hospital, IHACC Research Team, Katarina Ost*, Lea Berrang-Ford, Katherine Bishop-Williams, Margot Charette, Sherilee L. Harper, Shuaib Lwasa, Didacus B. Namanya, Yi Huang, Aaron B. Katz, Kristie Ebi

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

Background: There is concern in the international community regarding the influence of climate change on weather variables and seasonality that, in part, determine the rates of malaria. This study examined the role of sociodemographic variables in modifying the association between temperature and malaria in Kanungu District (Southwest Uganda). Methods: Hospital admissions data from Bwindi Community Hospital were combined with meteorological satellite data from 2011 to 2014. Descriptive statistics were used to describe the distribution of malaria admissions by age, sex, and ethnicity (i.e. Bakiga and Indigenous Batwa). To examine how sociodemographic variables modified the association between temperature and malaria admissions, this study used negative binomial regression stratified by age, sex, and ethnicity, and negative binomial regression models that examined interactions between temperature and age, sex, and ethnicity. Results: Malaria admission incidence was 1.99 times greater among Batwa than Bakiga in hot temperature quartiles compared to cooler temperature quartiles, and that 6–12 year old children had a higher magnitude of association of malaria admissions with temperature compared to the reference category of 0–5 years old (IRR = 2.07 (1.40, 3.07)). Discussion: Results indicate that socio-demographic variables may modify the association between temperature and malaria. In some cases, such as age, the weather-malaria association in sub-populations with the highest incidence of malaria in standard models differed from those most sensitive to temperature as found in these stratified models. Conclusion: The effect modification approach used herein can be used to improve understanding of how changes in weather resulting from climate change might shift social gradients in health.

Original languageEnglish
Article number98
JournalMalaria Journal
Volume21
Issue number1
DOIs
Publication statusPublished - 22 Mar 2022
Externally publishedYes

Bibliographical note

Funding Information:
Thank you to Carlee Wright, the project manager of IHACC for creating the map in this manuscript, and to the Thomas Francis Jr. Fellowship. Finally, thank you to Samuel Des Rochers-Jette for his coding support.

Publisher Copyright:
© 2022, The Author(s).

Fingerprint

Dive into the research topics of 'Do socio-demographic factors modify the effect of weather on malaria in Kanungu District, Uganda?'. Together they form a unique fingerprint.

Cite this