Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis

M Siopi; N Siafakas; S Vourli; Johan Mouton; L Zerva; Joseph Meletiadis

doi:10.1093/jac/dkw276

Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis

M Siopi, N Siafakas, S Vourli, Johan Mouton, L Zerva, Joseph Meletiadis

Medical Microbiology & Infectious Diseases

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	3135-3147
Number of pages	13
Journal	Journal of Antimicrobial Chemotherapy
Volume	71
Issue number	11
DOIs	https://doi.org/10.1093/jac/dkw276
Publication status	Published - 2016

Research programs

EMC MM-04-28-01

Access to Document

10.1093/jac/dkw276

Cite this

Siopi, M., Siafakas, N., Vourli, S., Mouton, J., Zerva, L., & Meletiadis, J. (2016). Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis. Journal of Antimicrobial Chemotherapy, 71(11), 3135-3147. https://doi.org/10.1093/jac/dkw276

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title = "Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis",

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year = "2016",

doi = "10.1093/jac/dkw276",

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Siopi, M, Siafakas, N, Vourli, S, Mouton, J, Zerva, L & Meletiadis, J 2016, 'Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis', Journal of Antimicrobial Chemotherapy, vol. 71, no. 11, pp. 3135-3147. https://doi.org/10.1093/jac/dkw276

Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis. / Siopi, M; Siafakas, N; Vourli, S et al.
In: Journal of Antimicrobial Chemotherapy, Vol. 71, No. 11, 2016, p. 3135-3147.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Siopi, M

AU - Siafakas, N

AU - Vourli, S

AU - Mouton, Johan

AU - Zerva, L

AU - Meletiadis, Joseph

PY - 2016

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Siopi M, Siafakas N, Vourli S, Mouton J, Zerva L, Meletiadis J. Dose optimization of voriconazole/anidulafungin combination against Aspergillus fumigatus using an in vitro pharmacokinetic/pharmacodynamic model and response surface analysis: clinical implications for azole-resistant aspergillosis. Journal of Antimicrobial Chemotherapy. 2016;71(11):3135-3147. doi: 10.1093/jac/dkw276