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EACTS Expert Consensus Statement on the Ross Procedure in Adult Patients

  • Jan Vojacek*
  • , Jan Gofus
  • , EACTS Scientific Document Group
  • , Martin Andreas
  • , Joseph E. Bavaria
  • , Denis Berdajs
  • , Filip P.A. Casselman
  • , Ismail El-Hamamsy
  • , Tomas Holubec
  • , Laurent de Kerchove
  • , Milan Milojevic
  • , Leonardo Mulinari
  • , Maral Ouzounian
  • , Peter Skillington
  • , Johanna J.M. Takkenberg
  • , Peter Verbrugghe
  • *Corresponding author for this work
  • Charles University
  • Medical University of Graz
  • Thomas Jefferson University
  • University of Basel
  • AZORG
  • Icahn School of Medicine at Mount Sinai
  • University Hospital Frankfurt am Main
  • Cliniques Universitaires Saint-Luc
  • Dedinje Cardiovascular Institute
  • University of Zurich
  • University of Miami
  • Peter Munk Cardiac Centre
  • Epworth HealthCare
  • University Hospitals Leuven

Research output: Contribution to journalReview articleAcademicpeer-review

14 Citations (Scopus)
3 Downloads (Pure)

Abstract

The Ross procedure, which involves replacing a diseased aortic valve with the patient’s own pulmonary valve (pulmonary autograft), has gained renewed attention in adult patients due to mounting evidence of excellent long-term outcomes. With increasing data demonstrating restoration of life expectancy and improved valve-related outcomes, it is now considered a viable first-line option for selected young and middle-aged adults with non-repairable aortic valve disease. Nonetheless, its adoption remains inconsistent across institutions, partly due to concerns about surgical complexity, long-term durability, and the need for structured follow-up. This expert consensus document, commissioned by the European Association for Cardio-Thoracic Surgery, synthesizes the current evidence and offers clinical statements for using the Ross procedure in adults. Developed through a systematic review and informed by the collective experience of a multidisciplinary panel of internationally recognized experts, the document addresses key topics including patient selection, technical refinements, and perioperative management. Emphasis is also placed on the need for procedural standardization, high-volume surgical expertise, and longitudinal imaging-based follow-up. Moreover, comparative outcome data and subgroup considerations are critically appraised, and areas for future investigation are outlined. This clinical practice document is intended to assist clinicians and Heart Teams in making informed treatment decisions, support harmonized implementation across centres, provide technical considerations to optimize procedural success, and substantially improve outcomes for patients considered for this complex but promising procedure.

Original languageEnglish
Article numberezaf295
JournalEuropean Journal of Cardio-thoracic Surgery
Volume68
Issue number2
DOIs
Publication statusPublished - Feb 2026

Bibliographical note

Publisher Copyright:
© European Association for Cardio-Thoracic Surgery 2025.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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