Echtzeit-registrierung der flussabhängigen dilatation der A. brachialis zur endothelfunktionsbestimmung

F. Stifft; R. Dammers; J. Tordoir; A. Hoeks

doi:10.1055/s-2003-37415

Echtzeit-registrierung der flussabhängigen dilatation der A. brachialis zur endothelfunktionsbestimmung

Translated title of the contribution: Real-time registration of flow-mediated dilatation for the assessment of endothelial function

F. Stifft
, R. Dammers
, J. Tordoir
, A. Hoeks^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

1 Citation (Scopus)

Abstract

Flow-mediated dilatation (FMD) is used to qualify vascular endothelial function. Aim: To evaluate the feasibility of real-time assessment of the stimulus-to-response (i. e. flow-velocity-to-diameter) relationship, repeated FMD was assessed in healthy subjects. Methods: Brachial artery diameter and flow velocity were measured simultaneously in 10 healthy male subjects lying in the supine position. These parameters were registered in real-time mode and beat-to-beat by means of a 7.5 MHz linear array transducer attached to a custom-built Wall Track System and an 8 MHz continuous wave Doppler. Results: Post-ischaemic increase in arterial diameter amounted to 5.9 ± 2.9% with an average increase in blood flow velocity of 487 ± 174%. The relative change in diameter was not correlated to the relative increase in flow velocity. Conclusion: Continuous registration of FMD can be performed. Motion artefacts, however, interfere with the realtime registration of FMD.

Translated title of the contribution	Real-time registration of flow-mediated dilatation for the assessment of endothelial function
Original language	German
Pages (from-to)	34-39
Number of pages	6
Journal	Ultraschall in der Medizin
Volume	24
Issue number	1
DOIs	https://doi.org/10.1055/s-2003-37415
Publication status	Published - Feb 2003
Externally published	Yes

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Cite this

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title = "Echtzeit-registrierung der flussabh{\"a}ngigen dilatation der A. brachialis zur endothelfunktionsbestimmung",

abstract = "Flow-mediated dilatation (FMD) is used to qualify vascular endothelial function. Aim: To evaluate the feasibility of real-time assessment of the stimulus-to-response (i. e. flow-velocity-to-diameter) relationship, repeated FMD was assessed in healthy subjects. Methods: Brachial artery diameter and flow velocity were measured simultaneously in 10 healthy male subjects lying in the supine position. These parameters were registered in real-time mode and beat-to-beat by means of a 7.5 MHz linear array transducer attached to a custom-built Wall Track System and an 8 MHz continuous wave Doppler. Results: Post-ischaemic increase in arterial diameter amounted to 5.9 ± 2.9\% with an average increase in blood flow velocity of 487 ± 174\%. The relative change in diameter was not correlated to the relative increase in flow velocity. Conclusion: Continuous registration of FMD can be performed. Motion artefacts, however, interfere with the realtime registration of FMD.",

author = "F. Stifft and R. Dammers and J. Tordoir and A. Hoeks",

year = "2003",

month = feb,

doi = "10.1055/s-2003-37415",

language = "German",

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issn = "0172-4614",

publisher = "Georg Thieme Verlag",

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AU - Stifft, F.

AU - Dammers, R.

AU - Tordoir, J.

AU - Hoeks, A.

PY - 2003/2

Y1 - 2003/2

N2 - Flow-mediated dilatation (FMD) is used to qualify vascular endothelial function. Aim: To evaluate the feasibility of real-time assessment of the stimulus-to-response (i. e. flow-velocity-to-diameter) relationship, repeated FMD was assessed in healthy subjects. Methods: Brachial artery diameter and flow velocity were measured simultaneously in 10 healthy male subjects lying in the supine position. These parameters were registered in real-time mode and beat-to-beat by means of a 7.5 MHz linear array transducer attached to a custom-built Wall Track System and an 8 MHz continuous wave Doppler. Results: Post-ischaemic increase in arterial diameter amounted to 5.9 ± 2.9% with an average increase in blood flow velocity of 487 ± 174%. The relative change in diameter was not correlated to the relative increase in flow velocity. Conclusion: Continuous registration of FMD can be performed. Motion artefacts, however, interfere with the realtime registration of FMD.

AB - Flow-mediated dilatation (FMD) is used to qualify vascular endothelial function. Aim: To evaluate the feasibility of real-time assessment of the stimulus-to-response (i. e. flow-velocity-to-diameter) relationship, repeated FMD was assessed in healthy subjects. Methods: Brachial artery diameter and flow velocity were measured simultaneously in 10 healthy male subjects lying in the supine position. These parameters were registered in real-time mode and beat-to-beat by means of a 7.5 MHz linear array transducer attached to a custom-built Wall Track System and an 8 MHz continuous wave Doppler. Results: Post-ischaemic increase in arterial diameter amounted to 5.9 ± 2.9% with an average increase in blood flow velocity of 487 ± 174%. The relative change in diameter was not correlated to the relative increase in flow velocity. Conclusion: Continuous registration of FMD can be performed. Motion artefacts, however, interfere with the realtime registration of FMD.

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Echtzeit-registrierung der flussabhängigen dilatation der A. brachialis zur endothelfunktionsbestimmung

Abstract

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