Ectopic retroviral expression of LMO2, but not IL2R gamma, blocks human T-cell development from CD34+cells: implications for leukemogenesis in gene therapy

Karin Overzet; D (Dirk) de Ridder; F (Floor) Weerkamp; Miranda Baert; Monique Verstegen; MH (Martijn) Brugman; SJ Howe; MJT Reinders; AJ Thrasher; Gerard Wagemaker; Jacques Dongen; Frank Staal

doi:10.1038/sj.leu.2404563

Ectopic retroviral expression of LMO2, but not IL2R gamma, blocks human T-cell development from CD34+cells: implications for leukemogenesis in gene therapy

Karin Overzet
, D (Dirk) de Ridder
, F (Floor) Weerkamp
, Miranda Baert
, Monique Verstegen
, MH (Martijn) Brugman
, SJ Howe
, MJT Reinders
, AJ Thrasher
, Gerard Wagemaker
, Jacques Dongen
, Frank Staal

Research output: Contribution to journal › Article › Academic › peer-review

70 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	754-763
Number of pages	10
Journal	Leukemia
Volume	21
Issue number	4
DOIs	https://doi.org/10.1038/sj.leu.2404563
Publication status	Published - 2007

Research programs

EMC MM-02-41-04
EMC MM-02-72-01

Access to Document

10.1038/sj.leu.2404563

http://hdl.handle.net/1765/36301

Cite this

Overzet, K., de Ridder, D., Weerkamp, F., Baert, M., Verstegen, M., Brugman, MH., Howe, SJ., Reinders, MJT., Thrasher, AJ., Wagemaker, G., Dongen, J., & Staal, F. (2007). Ectopic retroviral expression of LMO2, but not IL2R gamma, blocks human T-cell development from CD34+cells: implications for leukemogenesis in gene therapy. Leukemia, 21(4), 754-763. https://doi.org/10.1038/sj.leu.2404563

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title = "Ectopic retroviral expression of LMO2, but not IL2R gamma, blocks human T-cell development from CD34+cells: implications for leukemogenesis in gene therapy",

author = "Karin Overzet and \{de Ridder\}, \{D (Dirk)\} and Weerkamp, \{F (Floor)\} and Miranda Baert and Monique Verstegen and Brugman, \{MH (Martijn)\} and SJ Howe and MJT Reinders and AJ Thrasher and Gerard Wagemaker and Jacques Dongen and Frank Staal",

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Overzet, K, de Ridder, D, Weerkamp, F, Baert, M, Verstegen, M, Brugman, MH, Howe, SJ, Reinders, MJT, Thrasher, AJ, Wagemaker, G, Dongen, J & Staal, F 2007, 'Ectopic retroviral expression of LMO2, but not IL2R gamma, blocks human T-cell development from CD34+cells: implications for leukemogenesis in gene therapy', Leukemia, vol. 21, no. 4, pp. 754-763. https://doi.org/10.1038/sj.leu.2404563

TY - JOUR

T1 - Ectopic retroviral expression of LMO2, but not IL2R gamma, blocks human T-cell development from CD34+cells: implications for leukemogenesis in gene therapy

AU - Overzet, Karin

AU - de Ridder, D (Dirk)

AU - Weerkamp, F (Floor)

AU - Baert, Miranda

AU - Verstegen, Monique

AU - Brugman, MH (Martijn)

AU - Howe, SJ

AU - Reinders, MJT

AU - Thrasher, AJ

AU - Wagemaker, Gerard

AU - Dongen, Jacques

AU - Staal, Frank

PY - 2007

Y1 - 2007

U2 - 10.1038/sj.leu.2404563

DO - 10.1038/sj.leu.2404563

M3 - Article

C2 - 17268520

SN - 0887-6924

VL - 21

SP - 754

EP - 763

JO - Leukemia

JF - Leukemia

IS - 4

ER -