Editorial: Physical activity: a promising modifiable behavior to protect brain, cognition, and mental health across the lifespan

Physical activity is increasingly recognized as a pivotal modifiable behavior with significant impacts on physical health, brain function, cognition, and mental wellbeing throughout life. Despite overwhelming evidence supporting its positive effects, global physical activity levels remain alarmingly low, presenting a significant public health challenge. This Research Topic highlights the powerful role of physical activity in promoting brain health and mental wellbeing, focusing on cognitive function, emotional regulation, and psychological distress across diverse populations and life stages. It also provides insights into some mechanisms linking physical activity with brain health outcomes.